Chase Bourbon

A network for self-transcendence derived from patients with brain lesions

bioRxiv (Cold Spring Harbor Laboratory) March 27, 2026 Morgan Rose Healey, Yaser Sanchez-Gama, Mengyuan Ding et al. preprint

Abstract Self-transcendence, the reorientation of experience away from the self toward others, nature, or broader meaning, is a fundamental dimension of human psychology, yet its causal neural architecture remains poorly understood. Here we applied lesion network mapping to 88 neurosurgical patients with pre- and post-operative assessments of trait self-transcendence to identify the distributed...