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Zhenshuo Guo

2 papers in the library · 2 citations · publishing 2025

Papers

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Metabolism study of two phenethylamine - derived new psychoactive substances using in silico, in vivo, and in vitro approaches.

Archives of Toxicology March 10, 2025 Yiling Tang, Linhao Xu, Zhenshuo Guo et al. 1 citation

New psychoactive substances (NPS) are substances that are not controlled by international drug control conventions but are abused and pose a threat to public health. Proscaline and methallylescaline are two phenylethylamines with psychoactive and stimulant effects and are also derivatives of the classic hallucinogen mescaline. However, limited toxicity information on proscaline and...

Qualitative confirmation of 30 phencyclidine analogs in human blood and urine using GC-HRMS and a self-built library search.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences February 1, 2025 Zixuan Song, Zhenshuo Guo, Yiling Tang et al. 1 citation

Phencyclidine, a dissociative anesthetic with hallucinogenic effects, is commonly abused as a recreational drug. Phencyclidine analogs are compounds produced by substitutions of the phenyl and piperidine rings of phencyclidine. Illegal use of phencyclidine and its analogs has symptoms such as addiction, confusion, and increased tendencies toward violence. In this study, a novel high-throughput...