Application of mindfulness-based stress reduction plan in post-stroke patients with mild depression.
Frontiers in Neurology January 1, 2025 Xiaofei Pang, Dong Qiu, Xiaowen He et al.
In patients with post-stroke mild depression, adding mindfulness-based stress reduction to conventional intervention therapy improved depression and cognitive outcomes more than conventional therapy alone. Eighty patients were randomly assigned to either conventional therapy alone or conventional therapy plus an 8-week mindfulness-based stress reduction plan. Both groups showed reduced depression scores (HAMD-17, SDS) and inflammatory markers (TNF-α, hs-CRP, IL-6) and improved cognitive scores (MMSE, MoCA) after treatment. The combination group had significantly lower depression scores and inflammatory factor levels and significantly higher cognitive scores than the control group. The authors conclude that the combined approach improves overall response rate and has a significant advantage in reducing depression.