Real-time fMRI neurofeedback modulates auditory cortex activity and connectivity in schizophrenia patients with auditory hallucinations: A controlled study.
Psychiatry Research Neuroimaging October 1, 2025 Clemens C C Bauer, Jiahe Zhang, Francesca Morfini et al.
Auditory hallucinations (AHs) affect 60-80 % of schizophrenia patients and often resist antipsychotic treatment. AHs involve superior temporal gyrus (STG) hyperactivity and disrupted auditory-cognitive control connectivity. Real-time fMRI neurofeedback (NFB) enables voluntary modulation of targeted brain regions. We previously showed STG-targeted NFB with mindfulness meditation reduced STG...
DOI: 10.1016/j.pscychresns.2025.112050 (opens in new tab)
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Default mode network
Mindfulness
Dorsolateral prefrontal cortex
Superior temporal gyrus