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Monika Klírová

1 paper in the library · 46 citations · publishing 2020

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The Antidepressant Effect of Ketamine Is Dampened by Concomitant Benzodiazepine Medication

Frontiers in Psychiatry August 28, 2020 Veronika Andrashko, Tomáš Novák, Martin Brunovský et al. 46 citations

The rapid antidepressant effect of ketamine has become a breakthrough in the research and treatment of depression. Although predictive and modulating factors of the response to ketamine are broadly studied, little is known about optimal concurrent medication protocols. Concerning gamma-aminobutyric acid neurotransmission being a shared target for both ketamine and benzodiazepines (BZD), we...