Effect of Concomitant Benzodiazepines on the Antidepressant Effects of Ketamine
The Journal of Clinical Psychiatry November 14, 2022 Anna Feeney, Bettina B. Hoeppner, Marlene P. Freeman et al. 9 citations
Objective: Ketamine is a novel and rapidly acting treatment for major depressive disorder (MDD). Benzodiazepines are commonly coprescribed with antidepressants in MDD. This study sought to examine data from a randomized clinical trial that compared a single infusion of intravenous (IV) ketamine to midazolam placebo in treatment-resistant depression (DSM-IV-TR MDD) and to assess whether the use...