Rapid modulation of spine morphology by the 5-HT 2A serotonin receptor through kalirin-7 signaling
Proceedings of the National Academy of Sciences November 4, 2009 Kelly A. Jones, Deepak P. Srivastava, John Allen et al. 215 citations
The 5-HT(2A) serotonin receptor is the most abundant serotonin receptor subtype in the cortex and is predominantly expressed in pyramidal neurons. The 5-HT(2A) receptor is a target of several hallucinogens, antipsychotics, anxiolytics, and antidepressants, and it has been associated with several psychiatric disorders, conditions that are also associated with aberrations in dendritic spine...