Ketamine alters oscillatory coupling in the hippocampus
Scientific Reports August 2, 2013 Fábio V. Caixeta, Alianda Maira Cornélio, Robson Scheffer-Teixeira et al. 134 citations
Recent studies show that higher order oscillatory interactions such as cross-frequency coupling are important for brain functions that are impaired in schizophrenia, including perception, attention and memory. Here we investigated the dynamics of oscillatory coupling in the hippocampus of awake rats upon NMDA receptor blockade by ketamine, a pharmacological model of schizophrenia. Ketamine (25,...