Ciprofol is a novel GABAergic intravenous anesthetic with a rapid onset and favorable safety profile; however, the neural mechanisms underlying the induction and reversal of unconsciousness remain unclear. Electroencephalogram (EEG) microstates provide millisecond-scale markers of large-scale brain network dynamics and may reveal frequency-specific signatures of ciprofol' s effects on...
Connected consciousness refers to the state when external stimuli can enter into the stream of our consciousness experience. Emerging evidence suggests that although patients may not respond behaviorally to external stimuli during anesthesia, they may be aware of their surroundings. In this work, we investigated whether EEG based brain decoding could be used for detecting connected...
Abstract Objective In this study, we comprehensively studied alternations of EEG microstates in resting state, light, and deep level of propofol-induced unconsciousness. We further investigated the feasibility of using microstate features for differentiating different consciousness levels. Methods 60-channel EEG was recorded from 31 male subjects in resting, light, and deep anesthesia states....