The effects of phencyclidine pretreatment on amphetamine-induced behavior and c-Fos expression in the rat.
Brain Research January 12, 2001 S M Turgeon, L C Case
Previous data demonstrate that a single injection of phencyclidine enhances amphetamine-induced behaviors 24 h later, suggesting that the delayed effects of a single dose of phencyclidine may produce a schizophrenia-like state in animals. These behavioral changes were accompanied by altered patterns of c-Fos induction, suggesting possible neurochemical correlates to the observed behaviors....