Reinforcing effects of extended inhalation of nitrous oxide in humans.
Drug and Alcohol Dependence February 1, 1993 Cathleen S. Dohrn, J L Lichtor, Dennis W. Coalson et al.
The subjective, psychomotor and reinforcing effects of nitrous oxide at subanesthetic doses (30% and 40% in oxygen) were determined in normal healthy volunteers using a choice paradigm. Thirty percent nitrous oxide was chosen no more often than oxygen (41.6% choice rate), indicating that, for most of the subjects tested, extended inhalation of this nitrous oxide concentration was no more...