Katie Trinci

THE EFFECTS OF ACUTE CANNABIS WITH AND WITHOUT CANNABIDIOL ON NEURAL REWARD ANTICIPATION IN ADULTS AND ADOLESCENTS

The International Journal of Neuropsychopharmacology February 1, 2025 Martine Skumlien, Tom P. Freeman, Daniel L. Hall et al.

Abstract Background Cannabis, and its main psychoactive compound tetrahydrocannabinol (THC), may alter the brain’ s reward system both acutely and over time. The endocannabinoid and reward systems mature during adolescence and adolescents may therefore respond differently to acute cannabis exposure compared with adults. Despite this, no previous functional magnetic resonance imaging (fMRI)...

DOI: 10.1093/ijnp/pyae059.114 (opens in new tab) Cannabidiol Cannabis Anticipation artificial intelligence Cognitive psychology +1

The acute effects of cannabis, with and without cannabidiol, on attentional bias to cannabis related cues: a randomised, double-blind, placebo-controlled, cross-over study

Psychopharmacology February 28, 2024 Daniel L. Hall, Will Lawn, Shelan Ofori et al. 5 citations

RATIONALE: Attentional bias to drug-related stimuli is hypothesised to contribute towards addiction. However, the acute effects of Δ9-tetrahydrocannabinol (THC) on attentional bias to cannabis cues, the differential response in adults and adolescents, and the moderating effect of cannabidiol (CBD) are unknown. OBJECTIVES: Our study investigated (1) the acute effects of vaporised cannabis on...

DOI: 10.1007/s00213-024-06543-7 (opens in new tab) Full text (opens in new tab) Cannabidiol Addiction Attentional bias Placebo +7

Associations between regular cannabis use and brain resting-state functional connectivity in adolescents and adults

Journal of Psychopharmacology July 29, 2023 Natalie Ertl, Will Lawn, Claire Mokrysz et al. 17 citations

BACKGROUND/AIM: Cannabis use is highly prevalent in adolescents; however, little is known about its effects on adolescent brain function. METHOD: = 70, 35 adolescents/35 adults). Pre-registered analyses examined the connectivity of seven major cortical and sub-cortical brain networks (default mode network, executive control network (ECN), salience network, hippocampal network and three striatal...

DOI: 10.1177/02698811231189441 (opens in new tab) Full text (opens in new tab) Cannabis Default mode network Resting State FMRI Functional connectivity +3

The acute effects of cannabis with and without cannabidiol in adults and adolescents: A randomised, double‐blind, placebo‐controlled, crossover experiment

Addiction February 8, 2023 Will Lawn, Katie Trinci, Claire Mokrysz et al. 36 citations

Abstract Background and Aims Long‐term harms of cannabis may be exacerbated in adolescence, but little is known about the acute effects of cannabis in adolescents. We aimed to (i) compare the acute effects of cannabis in adolescent and adult cannabis users and (ii) determine if cannabidiol (CBD) acutely modulates the effects of delta‐9‐tetrahydocannabinol (THC). Design Randomised, double‐blind,...

DOI: 10.1111/add.16154 (opens in new tab) Cannabis Cannabidiol Psychotomimetic Placebo +5

Validation of the Psychological Insight Scale: A new scale to assess psychological insight following a psychedelic experience.

J Psychopharmacol January 5, 2022 Joseph Peill, Katie Trinci, Hannes Kettner et al. 135 citations

Validation of the Psychological Insight Scale: A new scale to assess psychological insight following a psychedelic experience.

DOI: 10.1177/02698811211066709 (opens in new tab) Full text (opens in new tab) Psychedelic research Psychological insight Psychometric scale Therapeutic potential