Cannabis analgesia in chronic neuropathic pain is associated with altered brain connectivity
Neurology September 5, 2018 L. Weizman, Lior Dayan, Silviu Brill et al.
Objective To characterize the functional brain changes involved in δ-9-tetrahydrocannabinol (THC) modulation of chronic neuropathic pain. Methods Fifteen patients with chronic radicular neuropathic pain participated in a randomized, double-blind, placebo-controlled trial employing a counterbalanced, within-subjects design. Pain assessments and functional resting state brain scans were performed...