Amygdala activity contributes to the dissociative effect of cannabis on pain perception
Pain 2013 Michael Lee, M. Ploner, K. Wiech et al.
Summary fMRI evidence suggests that delta‐9‐tetrahydrocannabinol, the psychoactive component of cannabis, targets the affective aspects of pain in humans by altering the activity and functional connections of the amygdala. Abstract Cannabis is reported to be remarkably effective for the relief of otherwise intractable pain. However, the bases for pain relief afforded by this psychotropic agent...