My findings show what causes loss of awareness, anesthesia, memory replay, opioid induced respiratory depression (OIRD), and slow wave sleep. Opiates are fast pain relievers and anesthetics that can cause respiratory arrest. I found how mu-opioids and anesthetics by activating medial habenula (MHb) and/or interpeduncular nucleus (IPN) induce unawareness and slowdown respiration. Using DTI...
My findings show what causes loss of awareness, anesthesia, memory replay, opioid induced respiratory depression (OIRD), and slow-wave sleep (SWS). Opiates are fast pain relievers and anesthetics that can cause respiratory arrest. I found how mu-opioids and anesthetics by activating medial habenula (MHb) and/or interpeduncular nucleus (IPN) induce unawareness and slowdown respiration. MHb...
My findings show, for the first time, what causes loss of awareness, anesthesia, memory replay, opioids induced respiratory depression (OIRD), and slow wave sleep. Opiates are fast pain relievers and anesthetics that can cause respiratory arrest. I found how mu-opioids and other medial habenula activators slowdown respiration during SWS and anesthesia. Using DTI method I observed that human...
Opiates are fast pain relievers that can cause respiratory arrest.I show new mechanisms how mu-opioids and high prenatal nicotine cause respiratory slowdownlinked to slow wave sleep. Mu-opioids activate the medial habenula which activates theinterpeduncular nucleus. The MHb-IPN system decreases respiration and alarm/arousal response tohypercapnia by projections to PAG, DRN, MRN and...