Journal of Psychoactive Drugs
May 22, 2026
Fiona Low, Mitch Earleywine
Limited research suggests that distinct intentions covary with acute experiences and subsequent outcomes. Nevertheless, data on the types of intentions set by users remain scarce, and their effects lack clarity. This study uses a retrospective, mixed-methods, cross-sectional approach to investigate intention-setting among psychedelic users. We establish a taxonomy of intentions in naturalistic...
Journal of Psychoactive Drugs
October 8, 2025
Samantha G. Gomez, Fiona Low, Mitch Earleywine
Since its resurgence, psychedelic research has garnered considerable attention, especially in mental health. Preliminary findings have indicated positive results regarding psychedelic-assisted psychotherapy. Despite promising findings, various researchers have voiced concerns regarding psychedelic research and its potential for volunteer bias. Participants willing to participate in clinical...
J Psychoactive Drugs
October 30, 2024
Mitch Earleywine, Genevieve S. Falabella, Alyssa B. Oliva et al.
3 citations
Acute Psychedelic Reactions, Post-Acute Changes in Dysfunctional Attitudes, and Psychedelic-Associated Changes in Wellbeing.
Journal of Psychedelic Studies
July 11, 2024
Alyssa B. Oliva, Mitch Earleywine, Fiona Low et al.
AbstractBackground and AimsResearch on psychedelic-assisted therapy (PAT), a promising treatment option for major depression, has not revealed if potential clients show preferences about the demographic characteristics of providers comparable to those common in other forms of psychotherapy. Previous work suggests that honoring comparable client preferences can enhance therapeutic outcomes. This...
Journal of Psychopharmacology
December 4, 2023
Maha N. Mian, Brianna R. Altman, Fiona Low et al.
8 citations
Background: Individuals who use psychedelics take efforts to mitigate unintended consequences. Despite the demonstrated utility of analogous protective behavioral strategies (PBS) assessments for other substances, no standardized scale exists to capture these protective strategies for psychedelic use. Objective: The present study addresses a notable gap concerning the assessment of psychedelic...
Journal of Psychoactive Drugs
June 21, 2023
Fiona Low, Mitch Earleywine
15 citations
Grief, a common reaction to loss, can frequently become problematic or impairing. Available treatments for prolonged grief disorder are promising but leave room for considerable improvement. Qualitative accounts of psychedelic experiences after bereavement reveal themes that parallel core components of prolonged grief disorder therapy. However, few studies have investigated the therapeutic...
Journal of Psychoactive Drugs
January 22, 2023
Fiona Low, Mitch Earleywine
3 citations
Patient-perceived treatment credibility is linked to important outcome measures including symptom reduction, therapeutic alliance, patient satisfaction, and attrition rates. However, few studies have tested strategies to enhance treatment credibility. The present study investigates the effect of brief, written educational materials and the use of an image induction prime on perceptions of...
Journal of Humanistic Psychology
April 2, 2022
Mitch Earleywine, Fiona Low, Carmen Lau et al.
47 citations
Integration therapy, an integral part of psychedelic-assisted treatment, usually includes sessions devoted to making meaning of relevant psychedelic experiences after subjective effects have subsided. As the psychedelic renaissance continues, offers for this integration therapy have proliferated. In the present project, semi-structured interviews with 30 integration therapists focused on...
Journal of Psychoactive Drugs
March 23, 2022
Mitch Earleywine, Fiona Low, Brianna R. Altman et al.
31 citations
Promising outcomes of Psilocybin-Assisted Therapy (PAT) for depression have generated concerted efforts to replicate, extend, and refine protocols to maximize efficacy. Psychotherapy research reveals that clients benefit most when important components of treatment align with their personal preferences. One open question related to PAT concerns the importance of the psilocybin experience of the...