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Richard A.E. Edden

2 papers in the library · 48 citations · publishing 2014-2025

Papers

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Glutamate plus glutamine to GABA ratio as a predictor of ketamine response in treatment-resistant depression: A double-blind, randomized, open-label extension study.

Journal of Affective Disorders August 15, 2025 Yohei Ohtani, Hideaki Tani, Shiori Honda et al. 3 citations

Approximately 30 % of patients with treatment-resistant depression (TRD) respond to ketamine; however, no replicable predictors of response have been reported. The imbalance between excitatory and inhibitory neurotransmissions may be implicated in the mechanism of action of ketamine. This study aimed to evaluate whether the ratio of glutamate and glutamine (Glx) to GABA levels at baseline in...

Enhanced Awareness Followed Reversible Inhibition of Human Visual Cortex: A Combined TMS, MRS and MEG Study

PLoS One June 23, 2014 Christopher Allen, Benjamin T. Dunkley, Suresh Muthukumaraswamy et al. 45 citations

This series of experiments investigated the neural basis of conscious vision in humans using a form of transcranial magnetic stimulation (TMS) known as continuous theta burst stimulation (cTBS). Previous studies have shown that occipital TMS, when time-locked to the onset of visual stimuli, can induce a phenomenon analogous to blindsight in which conscious detection is impaired while the...