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Stephen M. Liebowitz

2 papers in the library · 35 citations · publishing 1978

Papers

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Serotonin Receptor Binding Affinities of Several Hallucinogenic Phenylalkylamine and N,N-Dimethyltryptamine Analogues

Journal of Medicinal Chemistry 1978 Richard A Glennon, Stephen M. Liebowitz, Elizabeth C. Mack 35 citations

Hallucinogenic phenylalkylamine and N,N-dimethyltryptamine analogues are known to affect serotonergic systems both in vivo and in vitro. Using a rat stomach fundus model, the 5-HT receptor binding affinities of several of these analogues were determined and compared. The most behaviorally potent analogues examined, DOB, DOM, and 5-methoxy-N,N-dimethyltryptamine, were found to possess rather...