(±)3,4-methylenedioxymethamphetamine ("ecstasy") treatment modulates expression of neurotrophins and their receptors in multiple regions of adult rat brain.
The Journal of Comparative Neurology August 1, 2012 Ann M. Hemmerle, Jonathan W. Dickerson, Nicole R Herring et al. 29 citations
(±)3,4-Methylenedioxymethamphetamine (MDMA), a widely used drug of abuse, rapidly reduces serotonin levels in the brain when ingested or administered in sufficient quantities, resulting in deficits in complex route-based learning, spatial learning, and reference memory. Neurotrophins are important for survival and preservation of neurons in the adult brain, including serotonergic neurons. In...
DOI: 10.1002/cne.23048 (opens in new tab)
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Substantia nigra
Hippocampus
Neostriatum
Cerebral cortex
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