Lysergic acid diethylamide reverses aging- and neurodegeneration-associated brain transcriptional programs
bioRxiv May 29, 2026 Aurora Savino, Carla Liaci, Ilaria Bertani et al.
Summary Psychedelic compounds such as lysergic acid diethylamide (LSD) are increasingly studied for their neuroplastic effects and potential relevance to brain aging and neurodegeneration. However, the molecular mechanisms linking psychedelic-induced plasticity to age-associated cognitive decline remain unclear. Brain aging and dementia are characterized by coordinated transcriptional programs...