Neuropsychologia
May 1, 2025
Carissa L. Philippi, J. Bruss, Carrie Shea et al.
Depressive disorders have been consistently associated with elevated levels of mind-wandering and self-focused negative rumination. Separate tracks of research have implicated brain structures within the default mode network (DMN) in both mind-wandering and depression. In this study, we hypothesized that diminished mind-wandering and fewer depressive symptoms would co-occur in individuals with...
Journal of Neuroscience Research
November 20, 2019
Carissa L. Philippi, J. Bruss, Aaron D. Boes et al.
Functional neuroimaging research has consistently associated brain structures within the default mode network (DMN) and frontoparietal network (FPN) with mind‐wandering. Targeted lesion research has documented impairments in mind‐wandering after damage to the medial prefrontal cortex (mPFC) and hippocampal regions associated with the DMN. However, no lesion studies to date have applied lesion...
Psychophysiology
October 1, 2019
Sahib S. Khalsa, David Rudrauf, Mahlega S Hassanpour et al.
Meditation is commonly assumed to be associated with enhanced interoceptive accuracy. We previously found that experienced meditators did not exhibit a greater ability than nonmeditators to detect heartbeat sensations at rest, despite the meditators' reported subjective ratings of higher accuracy and lower difficulty. Here, attempting to overcome previous methodological limitations, we assessed...
Frontiers in Psychology
July 7, 2015
Sahib S. Khalsa, David Rudrauf, Richard J. Davidson et al.
Meditation is commonly thought to induce physiologically quiescent states, as evidenced by decreased autonomic parameters during the meditation practice including reduced heart rate, respiratory rate, blood pressure, skin conductance, and increased alpha activity in the electroencephalogram. Preliminary empirical support for this idea was provided in a case report by Dimsdale and Mills (2002),...
Social Cognitive and Affective Neuroscience
May 2, 2014
Carissa L. Philippi, Daniel Tranel, Melissa Duff et al.
152 citations
Functional neuroimaging studies have implicated the default mode network (DMN) in autobiographical memory (AM). Convergent evidence from a lesion approach would help clarify the role of the DMN in AM. In this study, we used a voxelwise lesion-deficit approach to test the hypothesis that regions of the DMN are necessary for AM. We also explored whether the neural correlates of semantic AM (SAM)...
Psychophysiology
May 22, 2008
Sahib S. Khalsa, David Rudrauf, Antonio Damasio et al.
276 citations
Attention to internal body sensations is practiced in most meditation traditions. Many traditions state that this practice results in increased awareness of internal body sensations, but scientific studies evaluating this claim are lacking. We predicted that experienced meditators would display performance superior to that of nonmeditators on heartbeat detection, a standard noninvasive measure...