The commonest psychedelic mushroom growing naturally in Britain, Psilocybe semilanceata, is known in English as the Liberty Cap. This name, which references an ancient Roman social practice, has caused considerable speculation in modern literature. This article provides a conclusive etymology for how a magic mushroom acquired this obscure name.
Acute and enduring adverse effects of psilocybin have been reported anecdotally, but have not been well characterized. For this study, 1993 individuals (mean age 30 yrs; 78% male) completed an online survey about their single most psychologically difficult or challenging experience (worst “bad trip”) after consuming psilocybin mushrooms. Thirty-nine percent rated it among the top five most...
In the current issue of the American Journal of Drug and Alcohol Abuse, Johnson et al. (1) provide long-term outcome data from a smoking cessation pilot study of a treatment model using 2–3 doses o...
Evidence based treatment for Substance use disorders (SUD) includes psychotherapy and pharmacotherapy. However, these are only partially effective. Hallucinogens, such as psilocybin, may represent potential new treatment options for SUD. This review provides a summary of (human) studies on the putative therapeutic effects of psilocybin, and discusses the receptor systems, brain regions and...
BACKGROUND: A recent open-label pilot study (N = 15) found that two to three moderate to high doses (20 and 30 mg/70 kg) of the serotonin 2A receptor agonist, psilocybin, in combination with cognitive behavioral therapy (CBT) for smoking cessation, resulted in substantially higher 6-month smoking abstinence rates than are typically observed with other medications or CBT alone. OBJECTIVES: To...
ChemInformJuly 1, 2016Silvia Bartolucci, Michele Mari, Giovanni Di Gregorio et al.
AbstractThe selective indole alkylation reaction applying the Ir‐catalyzed‐borrowing hydrogen methodology and using amino alcohols (II), (V), (VII) as suitable nitrogen‐containing electrophiles is reported.
On July 18th, section 21 of the Drugs Act 2005 came into force: as a result, magic mushrooms are now classified as a Class A drug under the Misuse of Drugs Act 1971. Following a brief look at magic mushrooms and their effects, this paper charts their usage throughout history, from Saharan tribes in ancient times, through the psychedelic revolution of the 1960s, to the boom in (recently halted)...
Objective: Schizophrenia patients have a higher prevalence of type 2 diabetes mellitus than the general population, and even first-episode, drug-naive (FEDN) patients with schizophrenia have shown a higher prevalence of impaired glucose tolerance (IGT) than the general population.We aimed to investigate the prevalence of abnormal glucose tolerance after glucose loading, and to examine the...
This study is an examination of the positive and persisting psychological and behavioral aftereffects in eight individuals who reported consumption of psilocybin-containing mushrooms. Mushrooms containing psilocybin have been used for healing and spiritual purposes for thousands of years, and the therapeutic applications of psilocybin were scientifically examined beginning in the mid-20th...