Addiction
April 20, 2025
Joseph J Palamar, Nina Abukahok, Patricia Acosta et al.
7 citations
'Tusi', also known as 'tusibí' or 'pink cocaine', is a drug concoction which previously emerged in Latin America and Europe and has recently acquired popularity in the United States (US). Consumers are often unaware that Tusi contains a mixture of ketamine and other drugs, and the concoction can be confused with 2C/2C-B (ring-substituted phenethylamines/4-bromo-2,5-dimethoxyphenethylamine) or...
Journal of Psychoactive Drugs
April 18, 2025
Damian Swieczkowski, Aleksander Kwaśny, Krzysztof Sadko et al.
1 citation
Ibogaine, a non-classical psychedelic, has gained increasing attention as a potential treatment for substance use disorders (SUD); however, a lack of commercial interest and safety-related concerns limit its clinical development. This cross-sectional study investigates the current landscape of clinical trials involving ibogaine, a non-classical psychedelic, focusing on its safety and efficacy....
Biology direct
April 10, 2025
Matteo Ardini, Francesco Angelucci, Francesca Rea et al.
The "psychedelic renaissance" is sparking growing interest in clinical research, along with a rise in clinical trials. Substances such as 3,4-methylenedioxymethamphetamine (MDMA), psilocybin and N,N-dimethyltryptamine (DMT) are involved. The focus of this paper is on indolethylamine N-methyltransferase (INMT), a crucial enzyme in the biosynthesis of key compounds, including DMT, which meets...
Journal of Humanistic Psychology
April 9, 2025
Danielle Leonard, Thomas R. Brooks
1 citation
Peak and mystical experiences can be seen as states of consciousness that exist on a spectrum of varying intensity and duration. They are often described as moments of profound joy, ecstasy, and awe that involve feelings of noetic quality, decreased self-salience, and heightened interconnectedness. The renewed interest in psychedelics as a potential tool for therapeutic intervention has been...
Emergency and Critical Care Medicine
April 7, 2025
Evanthia Asimakopoulou, Panagiotis Theodosis-Nobelos, Charalampos Triantis
1 citation
Abstract. Illness requiring critical care can lead to the development of posttraumatic stress disorder (PTSD), a complex mental health condition resulting from exposure to traumatic events. In the intensive care unit (ICU), the nature of interventions often contributes to a high incidence of PTSD, which is a significant component of post-intensive care syndrome (PICS). This article provides a...
Progress in Neuro-Psychopharmacology and Biological Psychiatry
April 2, 2025
Agnieszka Bysiek, Adam Wojtas, Izabela Szpręgiel et al.
10 citations
Psilocybin has various therapeutic effects in mental and psychological disorders, including depression and mood disorders, obsessive-compulsive disorders, substance addiction and anxiety. Pharmacodynamic properties of psilocybin depend on doses used and time after administration. The psilocybin dose range varies depending on whether it is used therapeutically or for recreational purposes in...
South Atlantic Quarterly
April 1, 2025
Joseph Christian Greer
10 citations
Scholarship on the global history of psychedelics is divided into two rival approaches. This article analyzes these approaches, emphasizing the way in which ideological biases on both sides have stymied serious research on the use of psychedelic substances across space and time, before introducing the empirical approach as an alternative. The most prevalent view, “pharmacological Calvinism,”...
European Psychiatry
April 1, 2025
Albino J Oliveira-Maia
1 citation
Abstract The potential of psychedelic substances to treat mental illness is of significant clinical and societal interest, leading to academic and industry-based research to test their effects. Partly, such research was conducted to fulfil requirements of government agencies such as the European Medicines Agency (EMA) and the Food and Drug Administration (FDA), that have started defining...
South Atlantic Quarterly
April 1, 2025
Ramzi Fawaz
This piece introduces the special issue of SAQ “Psychedelic Imaginaries,” which collates fresh and theoretically sophisticated humanist perspectives on the contemporary psychedelic renaissance. Recent interdisciplinary research into psychoactive substances like LSD (or “acid”), psilocybin (or “magic mushrooms”), and MDMA (or “ecstasy”) has repeatedly shown that the therapeutically beneficial...
European Psychiatry
April 1, 2025
Michel Sabé
3 citations
Introduction Persons with schizophrenia are currently excluded from psychedelic-assisted therapy due to concerns about psychedelic-induced acute or persistent psychotic symptoms. However, meta-analytic evidence of the precise risk for psychedelic-induced de novo and exacerbation of psychosis in people with pre-existing psychotic disorders is lacking. Objectives We conducted an overview of...