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MDMA research published in 2011

Page 7 of 7: studies 121 to 125 of 125, newest first. Back to the MDMA overview

Studies

High concentrations of MDMA ('ecstasy') and its metabolite MDA inhibit calcium influx and depolarization-evoked vesicular dopamine release in PC12 cells.

Neuropharmacology 2011 Laura Hondebrink, Jan Meulenbelt, Marieke Meijer et al.

The popular synthetic drug of abuse 3,4-methylenedioxymethampetamine (MDMA) and its metabolite 3,4-methylenedioxyamphetamine (MDA) act mainly on the serotonergic system, though they also increase the amount of extracellular dopamine (DA) in the brain, presumably via reversal of the membrane dopamine transporter (DAT). As the involvement of exocytotic DA release is debated, we investigated if...

Differential effects of cocaine and MDMA self-administration on cortical serotonin transporter availability in monkeys.

Neuropharmacology 2011 Robert W Gould, H Donald Gage, Matthew L Banks et al.

Cocaine self-administration alters brain dopaminergic and serotonergic function primarily in mesolimbic and prefrontal brain regions whereas 3,4-methylenedioxymethamphetamine (MDMA) self-administration predominately alters brain serotonergic function in a more widespread distribution across cortical regions. We previously reported that, compared to drug-naïve rhesus monkeys, self-administration...

Methaemoglobinemia Induced by MDMA?

Case reports in pulmonology 2011 L L W Verhaert

Case. A 45-year-old man with a blank medical history presented at the emergency room with dizziness and cyanosis. Physical examination showed cyanosis with a peripheral saturation (SpO(2)) of 85%, he did not respond to supplemental oxygen. Arterial blood gas analysis showed a striking chocolate brown colour. Based on these data, we determined the arterial methaemoglobin concentration. This was...