Journal of Psychoactive Drugs
January 22, 2023
Fiona Low, Mitch Earleywine
3 citations
Patient-perceived treatment credibility is linked to important outcome measures including symptom reduction, therapeutic alliance, patient satisfaction, and attrition rates. However, few studies have tested strategies to enhance treatment credibility. The present study investigates the effect of brief, written educational materials and the use of an image induction prime on perceptions of...
NPJ Parkinson's disease
January 21, 2023
Jojo Yan Yan Kwok, Edmond Pui Hang Choi, Janet Yuen-Ha Wong et al.
Clinical practice guidelines support resilience training and exercise for patients with Parkinson's disease (PD). This assessor-blinded, randomized clinical trial aimed to compare the effects of a modified mindfulness meditation program versus stretching and resistance training exercise (SRTE) in patients with mild-to-moderate PD. A total of 126 potential participants were enrolled via...
International journal of adolescent medicine and health
January 20, 2023
Nilson Vieira Pinto, Moreira Sarmento Vivianne Dos Santos, R. Sousa et al.
Abstract Objectives Utility of cognitive-behavioral practice interventions in school settings have been discussed by the scientific community regarding their possibility of insertion in the educational field. In this way, this review article analyzes the scientific production on the practice of meditation offered at school in adolescents, since the appropriation of studies that point to...
Journal of Emotion and Psychopathology
January 20, 2023
Philippe R. Goldin, Amy E. Braun, Eve Ekman et al.
2 citations
Objectives: To investigate outcomes and predictors of a Tibetan Buddhist meditation process called Feeding Your Demons® (FYD) vs. a waitlist (WL) control group of meditation practitioners with moderate depression, anxiety, and stress symptoms. Methods: 61 meditators (70% female; mean age = 44.05, SD = 11.20; 43.5% White, 39% Asian, 9.3% Hispanic, 8.3% other) were randomly assigned to 1-month of...
Frontiers in Psychology
January 19, 2023
Kunhua Lee, Yu-Xuan Lee, Yu-Tung Cheng
ObjectivesThe pandemic has greatly impacted people’s lives and mental health. Therefore, it is now especially important to help people maintain good mental health. The positive effects of mindfulness-based practices on mental health have been demonstrated previously. However, no consensus has yet been reached on the potential mechanisms of mindfulness. This study adopted the two-component model...
Trials
January 19, 2023
Thorsten Barnhofer, Barnaby D. Dunn, Clara Strauss et al.
Background Major depression represents a pressing challenge for health care. In England, Increasing Access to Psychological Therapies (IAPT) services provide evidence-based psychological therapies in a stepped-care approach to patients with depression. While introduction of these services has successfully increased access to therapy, estimates suggest that about 50% of depressed patients who...
ACS Medicinal Chemistry Letters
January 18, 2023
Robert B. Kargbo
2 citations
The renaissance of research into psychedelics class of drugs has renewed interest for a possible psychedelic clinical therapy for treating psychiatric conditions such as treatment-resistant depression, major depressive-disorder, post-traumatic stress disorder, and other neuropsychiatric diseases. Psychedelics are known to stimulate neurogenesis and gliogenesis, reduce inflammation, and...
Journal of Psychedelic Studies
January 18, 2023
Benjamin R. Lewis, Kevin Byrne, John Hendrick et al.
22 citations
Abstract Background Psilocybin-assisted psychotherapy has demonstrated significant promise as a treatment for depression, anxiety, and existential distress associated with serious medical illness and has generally been employed on an individual basis, which presents challenges for scaling and resource availability. There are also compelling theoretical reasons to suggest that group-based...
bioRxiv
January 16, 2023
Anastasiya Zaytseva, Evelina Bouckova, McKennon J. Wiles et al.
preprint
Ketamine is shown to enhance excitatory synaptic drive in the hippocampus, which is presumed to underlie its rapid antidepressant effects. Moreover, ketamine’s therapeutic actions are likely mediated by enhancing neuronal Ca2+ signaling. However, ketamine is a noncompetitive NMDA receptor (NMDAR) antagonist that inhibits excitatory synaptic transmission and postsynaptic Ca2+ signaling. Thus, it...
Anxiety, Stress, and Coping
January 13, 2023
Maarten C. Eisma, Antje Janshen, Lukas S. Huber et al.
24 citations
BACKGROUND AND OBJECTIVES: Maladaptive emotion regulation strategies increase prolonged grief and depressive symptoms following bereavement. However, less is known about the role of adaptive emotion regulation strategies in adaptation to loss. Therefore, we examined the concurrent and longitudinal associations of three putative adaptive emotion regulation strategies (cognitive reappraisal,...