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Depression: all studies

Page 176 of 1,034: studies 1,751 to 1,760 of 10,336, newest first. Back to the depression overview

Research

A single dose of ketamine enhances early life stress-induced aggression with no effect on fear memory, anxiety-like behavior, or depression-like behavior in mice

Behavioral Neuroscience June 15, 2023 Caitlyn J Bartsch, Sophia Aaflaq, Jessica T. Jacobs et al.

Ketamine is a dissociative anesthetic that has been shown to have antidepressant effects in humans and has been proposed as a potential treatment for mood disorders such as PTSD and aggression. However, previous studies from our lab and others have demonstrated that ketamine’s effects are highly context- and dose-dependent. In a recent study, we found that 10 mg/kg ketamine could exacerbate the...

Case report: Improvement in refractory functional seizures, depression, and quality of life with ketamine-assisted therapy

Frontiers in Neuroscience June 12, 2023 Elena Argento, Egiroh Omene, Alexandra Jaeger et al. 10 citations

Functional seizures, a primary subtype of functional neurological disorder (FND), are a known cause of serious neurological disability with an increasing awareness of their impact amongst the neuroscience community. Situated at the intersection of neurology and psychiatry, FND is characterized by a range of alterations in motor, sensory or cognitive performance, such as abnormal movements, limb...

Self-treatment of parental neglect-induced mixed anxiety and depressive disorder with psilocybin – A retrospective case study

June 9, 2023 Mika Turkia 3 citations preprint

This article presents the case of a young woman in her mid-twenties with a history of depression since childhood. She lived with a mother who failed to take care of her. The patient cared for the emotional needs of the mother instead of the mother caring for the daughter's needs. Her father was mostly absent. Already around the age of thirteen, the patient was severely depressed and was...

The mediating role of depression and anxiety on the relationship between mindfulness and college adjustment

British Journal of Guidance & Counselling June 8, 2023 Fuat Can Çalışkan, Sibel Akmehmet-Şekerler, Zeynep Kızıltepe et al.

ABSTRACT Along with anxiety and depression, mindfulness has recently gained attention among the predictors of college adjustment. This study conducted in Türkiye, investigated the relationship between mindfulness and college adjustment through the mediating role of depression and anxiety. Data were collected using the Depression Anxiety Stress Scale, the Mindful Attention Awareness Scale, and...

Major depression disorder - etiology and treatment

Journal of Education, Health and Sport June 7, 2023 Paulina Czuchryta, Rafał Babiak, Karolina Bajak et al.

Introduction and purpose: The problem of major depression disorder (MDD) affects more and more people. In a few years, it may become the most common disease after cardiovascular diseases and cancer. MDD are manifested by a depressed mood, decreased energy, loss of interest and the ability to enjoy life, as well as a number of other additional symptoms. Untreated MDD can lead to disability. This...

The Role of Ketamine in the Treatment of Bipolar Depression: A Scoping Review.

Brain Sciences June 4, 2023 Muhammad Youshay Jawad, Saleha Qasim, Menglu Ni et al. 46 citations

Bipolar depression remains a clinical challenge with a quarter of patients failing to respond to initial conventional treatments. Although ketamine has been extensively studied in unipolar depression, its role in bipolar disorder remains inconclusive. The aim of our scoping review was to comprehensively synthesize the current clinical literature around ketamine use in bipolar depression. A...

DOI: 10.3390/brainsci13060909 (opens in new tab) Full text (opens in new tab) Ketamine Bipolar depression Bipolar disorder Mood disorders +1

Intranasal esketamine as therapeutic option: a case report of an adolescent with treatment resistant depression.

Frontiers in Psychiatry June 2, 2023

Depression is among the most common mental health disorders worldwide and treatment resistant depression (TRD) represents a major challenge for both patients and clinicians. In recent years ketamine has received attention as an antidepressant agent, demonstrating promising results in TRD in adults. To date, few attempts have been made in treating adolescent TRD with ketamine and none have used...

Psilocybin therapy: A novel approach to treating depression

International Journal of Surgery Global Health June 2, 2023 Tooba Noor, Areej Shakil, Aimen Waqar Khan et al.

The COVID-19 pandemic has resulted in a surge in depression cases, a pervasive and debilitating mental illness1. This trend is evident in the increased prescriptions for antidepressants. Depression is a chronic condition that affects a significant proportion of the global population, with ~280 million people, or about 3.8%, suffering from it. As a result, it is a significant mental health...

Ketamine Augmentation of Electroconvulsive Therapy: A Scoping Review of Dose-Dependent Effects in Major Depressive Disorder.

Cureus June 2023 Tarika Nagi, Amit Jagtiani, Saurabh Somvanshi et al.

Intravenous ketamine infusions in subanesthetic doses have been shown to rapidly alleviate depressive symptoms. However, the efficacy of ketamine as an anesthetic during electroconvulsive therapy (ECT) for major depression has not yet been answered by a large randomized control trial (RCT). This scoping review aims to examine the available literature to determine whether the dose of ketamine...

DOI: 10.7759/cureus.40087 (opens in new tab) Full text (opens in new tab) Treatment-resistant depression Depression ketamine Ect anesthesia Electroconvulsive therapy ect +5