The Future of Pain Management.
Pravarakhya Puppalla, Tara Menon Pattilachan, Rodrigo Salmeron de Toledo Aguiar, Charles E Argoff, Julie G Pilitsis
Neurologic Clinics August 1, 2025 DOI: 10.1016/j.ncl.2025.04.007 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Keywords | Acute pain Chronic pain Pain intervention Pain management Pain: pain Complex sensory Emotional And cognitive experience Effective pain treatment Transforming care Treatment algorithms Noninvasive neuromodulation Novel pain medication Psychedelics |
| Citations | 2 |
| Key findings | Progress in pain management includes advances in treatment algorithms, novel medications like ketamine, psychedelics, and cannabinoids, and noninvasive neuromodulation techniques. |
Abstract
This article explores the complexities of pain management, highlighting the multidimensional nature of pain, which encompasses affective, cognitive, and sensory experiences. The study examines the future of acute and chronic pain management through a thorough review of 3424 articles, ultimately including 143 relevant studies. Key findings indicate progress in treatment algorithms, novel medications (such as ketamine, psychedelics, and cannabinoids), and innovative approaches like noninvasive neuromodulation techniques. The article aims to outline current practices and exciting future research avenues, emphasizing the significant potential for new interventions in addressing the diverse causes of pain.