Skip to content

High-intensity mindfulness and cognitive behavioral group therapy for social anxiety disorder: Preliminary efficacy.

Shota Noda, Kentaro Shirotsuki, Yoshio Kodama, Mutsuhiro Nakao, Hisanobu Kaiya

PCN reports : psychiatry and clinical neurosciences December 7, 2025 DOI: 10.1002/pcn5.70264 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Pilot single-arm trial Randomized Peer reviewed
Sample size 10
Population Patients diagnosed with social anxiety disorder via structured clinical interview
Interventions Mindfulness and cognitive behavioral group therapy (M-CBT) comprising mindfulness training psychoeducation cognitive restructuring exposure exercises and group sharing
Duration Eight-session program with assessments at pre-intervention, mid-intervention, post-intervention, and follow-up
Topics Meditation Anxiety
Keywords Cognitive behavioral therapy Social anxiety disorder High‐intensity program
Key findings High-intensity group M-CBT was associated with improvements in social anxiety symptoms, cost and probability biases, depressive symptoms, subjective happiness, dispositional mindfulness, and cognitive reappraisal. Reductions in cost and probability biases from pre- to post-treatment and at follow-up had large effect sizes (cost bias d = 0.85–1.27; probability bias d = 1.07–2.42), whereas social anxiety symptom effects were moderate (d = 0.57–0.67). The authors suggest the format appears effective but call for randomized controlled trials.

Abstract

Aim: Cost and probability biases are known to predict improvements in symptoms of social anxiety disorder (SAD). This study developed a high-intensity mindfulness and cognitive behavioral group therapy (M-CBT) program-comprising mindfulness training, psychoeducation, cognitive restructuring, exposure exercises, and group sharing-designed to reduce these biases. The intervention was delivered in a group format, and its preliminary efficacy in patients with SAD was evaluated in a pilot single-arm trial.

Methods: Patients (N = 10) diagnosed with SAD through a structured clinical interview participated in an eight-session M-CBT program. They completed a set of questionnaires assessing SAD symptoms, cost and probability biases, fear of negative evaluation, self-focused attention, depressive symptoms, subjective happiness, dispositional mindfulness, cognitive reappraisal, and suppression at pre-intervention, mid-intervention, post-intervention, and follow-up.

Results: Analyses using linear mixed-effects models revealed that high-intensity M-CBT produced improvements in SAD symptoms, cost and probability biases, depressive symptoms, subjective happiness, dispositional mindfulness, and cognitive reappraisal (p < 0.05). The intervention also yielded significant reductions in cost and probability biases from pre- to post-treatment and at follow-up, with large effect sizes (cost bias: Cohen's d = 0.85-1.27; probability bias: d = 1.07-2.42). In contrast, the effect sizes for SAD symptoms were moderate (d = 0.57-0.67).

Conclusions: These findings suggest that high-intensity M-CBT can alleviate SAD symptoms and reduce cost and probability biases. Moreover, delivering M-CBT in a high-intensity format appears to be effective for individuals with SAD. Future randomized-controlled trials are warranted to more rigorously confirm these effects.

Comparable studies

Other non-randomized and open-label trials on anxiety, most cited first.

Study Year Design Participants
Quality of Acute Psychedelic Experience Predicts Therapeutic Efficacy of Psilocybin for Treatment-Resistant Depression Patients with treatment-resistant depression 2018 Clinical trial n = 20
Safety, Tolerability, and Efficacy of Psilocybin in 9 Patients With Obsessive-Compulsive Disorder Subjects with obsessive-compulsive disorder (OCD) 2006 Controlled clinical trial
Rapid Resolution of Suicidal Ideation After a Single Infusion of anN-Methyl-D-Aspartate Antagonist in Patients With Treatment-Resistant Major Depressive Disorder Subjects with DSM-IV-diagnosed treatment-resistant major depressive disorder 2010 Open-label trial n = 33
Emotions and brain function are altered up to one month after a single high dose of psilocybin. Healthy volunteers (7 female, 5 male) 2020 Open-label pilot study n = 12
Psilocybin-assisted group therapy for demoralized older long-term AIDS survivor men: An open-label safety and feasibility pilot study Older long-term AIDS survivor (OLTAS) self-identified gay men with moderate-to-severe... 2020 Open-label study

Citations in the library

Explore topics