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Mindfulness‐Based Interventions to Reduce Stress and Depression Among Midwives and Nurses: A Meta‐Analysis Study

Rongrong Zeng, Yan Zeng, Miao Li, Zhengtong Huangfu, Xiaoxia Zhang, Shulin Wang, Huan Liao

Worldviews on Evidence-Based Nursing February 1, 2026 DOI: 10.1111/wvn.70111 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Meta-analysis Peer reviewed
Sample size 4,612
Population Obstetrical nurses and midwives (2,904 in intervention groups, 1,708 in control groups across 55 studies)
Topics Depression Meditation
Key findings Mindfulness-based interventions were associated with significant reductions in stress (SMD = −0.71; 95% CI −0.97 to −0.44) and depression (SMD = −0.74; 95% CI −1.35 to −0.13) among nurses and midwives. Intervention duration significantly modified depression effects but not stress effects.

Abstract

ABSTRACT Background Mindfulness‐Based Interventions (MBIs) have gained traction in various healthcare settings, particularly for stress reduction among healthcare professionals. This meta‐analysis aimed to evaluate the effectiveness of MBIs on reducing stress and depression in obstetrical nurses.

Methods: A comprehensive literature search was done across multiple databases, including Cochrane Library, PsycINFO/PsycNet, PubMed/MEDLINE, Web of Science, and Google Scholar. The risk of bias for each included study was assessed using the Cochrane Risk of Bias Tool. Subgroup analyses were done according to intervention time (less than 8 weeks, 8 weeks, more than 8 weeks) and population. Meta‐analysis was done using random‐effects models. Effect sizes were calculated using standardized mean differences (SMD). Heterogeneity was assessed using the I 2 statistic.

Results: The sample size in 55 studies was 4612 nurses and midwives (2904 in the intervention group and 1708 in the control group). The meta‐analysis showed a significant overall effect of MBIs on reducing stress levels (SMD = −0.71; 95% CI [−0.97, −0.44]; p < 0.001), and depression (SMD = −0.74; 95% CI [−1.35, −0.13]; p < 0.001) among midwives and nurses. Subgroup analysis showed that the effects of intervention duration on reducing stress ( X 2 = 3.01, p = 0.220) was not significant, but its effect on depression ( X 2 = 61.46, p = 0.000) was significant. Linking Evidence to Action Healthcare organizations should integrate structured MBIs into staff wellness initiatives to promote mental well‐being. Nursing education programs can include mindfulness components to strengthen coping skills. Future work should also examine combined mindfulness–CBT programs (e.g., MINDBODYSTRONG) and address organizational factors contributing to burnout for a more comprehensive approach.

Comparable studies

Other systematic reviews and meta-analyses on meditation, most cited first.

Study Year Design Participants
Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations 2014 Meta-analysis n = 3,515
Mindfulness-Based Stress Reduction for Stress Management in Healthy People: A Review and Meta-Analysis Healthy subjects 2009 Systematic review and meta-analysis
The psychological effects of meditation: A meta-analysis. Nonclinical groups of adult meditators 2012 Meta-analysis n = 163
Efficacy of Mindfulness-Based Cognitive Therapy in Prevention of Depressive Relapse Adults with recurrent depression in full or partial remission 2016 Meta-analysis of individual patient data from randomized controlled trials n = 1,258
Mindfulness‐Based Stress Reduction and Mindfulness‐Based Cognitive Therapy – a systematic review of randomized controlled trials 2011 Systematic review

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