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Alcohol and marijuana effects on static visual acuity.

A J Adams, B Brown, M C Flom, R T Jones, A Jampolsky

American journal of optometry and physiological optics November 1975 DOI: 10.1097/00006324-197511000-00001 (opens in new tab)

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AI-extracted from the abstract
Characteristics Double-blind experiment Peer reviewed
Sample size 10
Population Ten human subjects
Interventions Alcohol Delta-9-tetrahydrocannabinol (THC) Placebo
Dose 0.5 ml and 1.0 ml/kg body weight of 95% ethanol; 8 and 15 mg delta-9-tetrahydrocannabinol (THC)
Duration Measurements up to six hours following drug ingestion
Measures static visual acuity
Topics Cannabis
Key findings Alcohol and THC produced no statistically significant change in static visual acuity at any dose or time point up to six hours after ingestion, at either 12% or 49% contrast. The authors contrast this with marked acuity decrements in the same subjects under the same drug conditions when targets were moving and required coordinated eye movements.

Abstract

Static visual acuity was measured at two contrast levels (12 and 49%) in ten subjects in a double blind experiment involving five drug conditions of alcohol and marijuana (0.5 ml and 1.0 ml/kg body weight of 95% ethanol, 8 and 15 mg delta-9-tetrahydrocannabinol (THC), and a placebo). We found no statistically significant change in static visual acuity for any of the dose levels at any of the measurement time up to six hours following drug ingestion; this is sharply contrasted with the marked decrements in acuity which were found in the same subjects under the same drug conditions when the targets were in motion and required corrdinated eye movements for their resolution.

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