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The Clinical and Dynamic Characteristics of Acute Psychosis Following the Use Synthetic Cannabinoids

Кекелидзе Зураб Ильич, Е.к. Карелина, Kozlov Alexandr Alexandrovich, S.M. Shakhova

American Journal of Psychiatry and Neuroscience October 23, 2018 DOI: 10.11648/j.ajpn.20180604.11 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational clinical study Peer reviewed
Sample size 173
Population Patients with psychotic conditions following synthetic cannabinoid use
Key findings The authors describe stages of psychosis after synthetic cannabinoid use and identify delirious, delirious-oneiroid, and amentia-like variants. They report that pathokinetic patterns are determined by clinical, biological, and socio-psychological factors, and that severity of clinical variants and consciousness disorders correlated positively with a progression from affective disorders through illusions, hallucinations, delusions, psychic automatism, and motor disorders, with gradual narrowing of the psychopathological picture.

Abstract

The article presents the results of research into the clinical and dynamic characteristics of psychosis following the use of synthetic cannabinoids (SC). The aim of the study is a clinical-dynamic analysis of 348 psychotic conditions following the use of synthetic cannabinoids involved 173 patients. The results of the study are: we describe the stages of psychosis development and psychosis delirious, delirious-oneiroid and amentia-like clinical variants; we demonstrated that the pathokinetic patterns of psychosis following SC use are determined by a complex of clinical, biological and socio-psychological factors; we found that the severity of clinical variants of the psychosis and consciousness disorders positively correlated with psychopathological conditions accompanied by more and more severe disorders of psychic activity (affective disorders – illusions and pareidolias – hallucinations – delusions – psychic automatism – ‘motor disorders) with simultaneous gradual depletion of psychosis psychopathologic picture resulting from the narrowing spectrum of psychopathological symptoms.