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Mindfulness for maternal health: A systematic umbrella review of effectiveness for addressing depression and anxiety symptoms

Elizabeth K. Stierman, Sarah Clifford, Briana E. Kramer, Melissa Soto, Mairead Minihane, Meighan Mary, Kathryn L. Spielman, Kirantheja Daggula, Andreea A. Creanga

Journal of Affective Disorders Reports October 11, 2026 DOI: 10.1016/j.jadr.2026.101194 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Systematic review Randomized Peer reviewed
Sample size 10,209
Population Pregnant and postpartum women
Intervention Mindfulness interventions
Topics Anxiety Depression Meditation
Key findings Meta-analyses in the included reviews tended to find beneficial effects of mindfulness on depressive and anxiety symptoms, with standardized mean differences ranging from no difference to relatively large effect sizes. The authors rate the evidence low to very low per GRADE criteria and conclude that mindfulness may reduce symptoms but that low-quality evidence and methodological concerns warrant caution.

Abstract

Objective: This umbrella review synthesizes evidence about the effectiveness of mindfulness interventions to improve mental health during pregnancy and postpartum.

Methods: We searched MEDLINE/PubMed, Scopus, Embase.com, PsycInfo, CINAHL, and the Cochrane Database of Systematic Reviews for systematic reviews published between January 1, 2015 and June 26, 2026. We included reviews of randomized controlled trials (RCTs) and non-randomized studies of interventions (NRSIs) assessing effects of mindfulness on depression or anxiety in pregnant and postpartum populations, with stress reported as a secondary outcome.

Results: We synthesized evidence from 25 systematic reviews encompassing 104 unique primary studies (72 RCTs and 32 NRSIs) and 10,209 study participants. The majority of studies assessed well-structured mindfulness programs, often facilitated over 4-8 weeks of group sessions. However, interventions were heterogenous and included both self-directed and facilitated approaches, delivered in-person and digitally. Fifteen reviews conducted meta-analyses. They tended to find evidence of beneficial effects on depressive and anxiety symptoms, with standardized mean differences between intervention and control groups ranging from no difference to relatively large effect sizes. Evidence was rated low to very low per GRADE criteria, due to concerns about the methodological quality of reviews, risk of bias in primary studies, significant heterogeneity, and small sample sizes.

Conclusion: Mindfulness interventions may reduce symptoms of depression and anxiety among pregnant and postpartum women. However, the low-quality of evidence and methodological concerns warrant caution when interpreting results.

Comparable studies

Other systematic reviews and meta-analyses on anxiety, most cited first.

Study Year Design Participants
Meditation Programs for Psychological Stress and Well-being Diverse adult clinical populations 2014 Meta-analysis n = 3,515
Research Review: The effects of mindfulness‐based interventions on cognition and mental health in children and adolescents – a meta‐analysis of randomized controlled trials Children and adolescents 2018 Systematic review and meta-analysis n = 3,666
Therapeutic effects of classic serotonergic psychedelics: A systematic review of modern‐era clinical studies Patients with cancer- or illness-related anxiety and depression, major depressive... 2020 Systematic review n = 188
Does Mindfulness Meditation Improve Anxiety and Mood Symptoms? A Review of the Controlled Research Clinical populations with medical and emotional disorders 2007 Systematic review n = 15
Antidepressive, anxiolytic, and antiaddictive effects of ayahuasca, psilocybin and lysergic acid diethylamide (LSD): a systematic review of clinical trials published in the last 25 years Patients from included clinical trials 2016 Systematic review

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