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Psychopathology and Pattern of Remission of Cannabis-Induced Psychotic Disorder

Pn Suresh Kumar, Vikas Menon, Rohith Suresh, Nalakath Arakkal Uvais

The Primary Care Companion For CNS Disorders April 14, 2023 DOI: 10.4088/pcc.22m03350 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Prospective cohort study Peer reviewed
Population Patients admitted with new-onset psychosis and cannabis use, with no evidence of other drug abuse, at a psychiatry inpatient department in Kerala, India
Duration Assessed at admission, after 1 week in hospital, and 1 month after discharge
Measures Structured Clinical Interview for the Positive and Negative Syndrome Scale, Clinical Global Impressions-Severity of illness scale
Topics Cannabis
Citations 1
Key findings The authors report that cannabis-induced psychosis in this Indian setting presents with predominant positive symptoms and minimal affective symptoms. Steady improvement after complete cessation of cannabis suggests a possible contributory role for cannabis in precipitating psychosis.

Abstract

To analyze the psychopathology and pattern of remission in cannabis-induced psychotic disorder with treatment. This was a prospective cohort study of a group of patients admitted with new-onset psychosis, cannabis use, and no evidence of other drug abuse from January 1 to June 31, 2019, to the psychiatry inpatient department of a multispecialty tertiary care hospital in Kerala, India. Patients were evaluated at admission and after 1 week in the hospital and 1 month after discharge using the Structured Clinical Interview for the Positive and Negative Syndrome Scale and the Clinical Global Impressions-Severity of illness scale. < .001). Cannabis-induced psychosis in the Indian setting presents with predominant positive symptoms and minimal affective symptoms. The steady improvement noted with complete cessation of cannabis indicates a possible contributory role for cannabis in precipitating psychosis.

Comparable studies

Other observational and cohort studies on cannabis, most cited first.

Study Year Design Participants
High-potency cannabis and the risk of psychosis People with first episode of psychosis and healthy controls from the local population 2009 Case-control study n = 454
Ayahuasca-Assisted Therapy for Addiction: Results from a Preliminary Observational Study in Canada Rural aboriginal population 2013 Observational study
Impaired cognitive performance in drug free users of recreational ecstasy (MDMA) Otherwise healthy young people 2000 Observational
Continued cannabis use and risk of incidence and persistence of psychotic symptoms: 10 year follow-up cohort study Individuals from the general population in Germany aged 14-24 at baseline 2011 Observational cohort n = 1,923
Cannabis-induced psychosis and subsequent schizophrenia-spectrum disorders: follow-up study of 535 incident cases Patients treated for cannabis-induced psychotic symptoms in Denmark between 1994 and... 2005 Observational cohort n = 535

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