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Cannabis and psychosis in acute psychiatric admissions

Robert F. Grace, Gillian Shenfield, Christopher C Tennant

Drug and Alcohol Review September 1, 2000 DOI: 10.1080/713659372 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational cohort Peer reviewed
Sample size 62
Population Acute psychiatric inpatients suspected of illicit drug use who had urinary drug screens
Topics Cannabis
Key findings THC-positive status was not significantly associated with psychosis or with length of admission, but THC-positive patients with recurrent psychosis were significantly younger and had a significantly shorter interval since last admission (10 months vs 33 months), suggesting faster relapse.

Abstract

Abstract: This study assessed the duration of admission and time to relapse in 62 acute psychiatric in‐patients who had urinary drug screens performed because of suspicion of illicit drug use. Some 51% of those with psychosis (n = 45) and 29% of those with non‐psychotic illness (n = 17) were THC‐positive although this was not significant. In those with recurrent admissions for psychosis tetrahydrocannabinol (THC)‐positive subjects were significantly younger. The duration of admission was 7 days shorter in the THC‐positive group but this was not significant. Their duration since last admission (rapidity of relapse) was 10 months versus 33 months which was significant.

Comparable studies

Other observational and cohort studies on cannabis, most cited first.

Study Year Design Participants
High-potency cannabis and the risk of psychosis People with first episode of psychosis and healthy controls from the local population 2009 Case-control study n = 454
Ayahuasca-Assisted Therapy for Addiction: Results from a Preliminary Observational Study in Canada Rural aboriginal population 2013 Observational study
Impaired cognitive performance in drug free users of recreational ecstasy (MDMA) Otherwise healthy young people 2000 Observational
Continued cannabis use and risk of incidence and persistence of psychotic symptoms: 10 year follow-up cohort study Individuals from the general population in Germany aged 14-24 at baseline 2011 Observational cohort n = 1,923
Cannabis-induced psychosis and subsequent schizophrenia-spectrum disorders: follow-up study of 535 incident cases Patients treated for cannabis-induced psychotic symptoms in Denmark between 1994 and... 2005 Observational cohort n = 535

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