Neurocognitive functions of heavy cannabis using schizophrenia patients
Shaul Lev-Ran, Aviv Segev, Yoram Braw, Yechiel Levkovitz
European Psychiatry June 28, 2011 DOI: 10.1016/j.eurpsy.2011.04.010 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational study Peer reviewed |
|---|---|
| Population | Schizophrenia patients with and without heavy cannabis use, and healthy controls, all negative for other substance use |
| Topics | Cannabis |
| Citations | 17 |
| Key findings | Schizophrenia patients performed worse than healthy controls across a broad range of neurocognitive tasks. Within the schizophrenia group, heavy cannabis users showed impairments concentrated on attention tasks, with response patterns suggesting impulsivity. |
Abstract
This current study assessed neurocognitive functioning in a carefully selected sample of schizophrenia patients with and without heavy cannabis use and healthy controls. All subjects were negative for any other substance use. Schizophrenia subjects had impaired neurocognitive functions across a wide range of tasks compared to healthy controls. Cannabis using schizophrenia patients had focused impairments on tasks of attention, and the findings suggest an impulsive pattern of response among these patients.
Comparable studies
Other observational and cohort studies on cannabis, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| High-potency cannabis and the risk of psychosis People with first episode of psychosis and healthy controls from the local population | 2009 | Case-control study | n = 454 |
| Ayahuasca-Assisted Therapy for Addiction: Results from a Preliminary Observational Study in Canada Rural aboriginal population | 2013 | Observational study | |
| Impaired cognitive performance in drug free users of recreational ecstasy (MDMA) Otherwise healthy young people | 2000 | Observational | |
| Continued cannabis use and risk of incidence and persistence of psychotic symptoms: 10 year follow-up cohort study Individuals from the general population in Germany aged 14-24 at baseline | 2011 | Observational cohort | n = 1,923 |
| Cannabis-induced psychosis and subsequent schizophrenia-spectrum disorders: follow-up study of 535 incident cases Patients treated for cannabis-induced psychotic symptoms in Denmark between 1994 and... | 2005 | Observational cohort | n = 535 |
Citations in the library
Cited by 4
- Cannabis, esquizofrenia y cognición, aportes de la conectividad cerebral Adicciones February 6, 2020
- Does cannabis affect cognitive functioning in patients with schizophrenia? Schizophrenia Research: Cognition December 20, 2023
- Meta-analysis of neurocognition in young psychosis patients with current cannabis use. Journal of Psychiatric Research April 1, 2018
- Effects of Extended Cannabis Abstinence on Cognitive Outcomes in Cannabis Dependent Patients with Schizophrenia vs Non-Psychiatric Controls. Neuropsychopharmacology October 2017
Cites 8
- Cannabidiol, a Cannabis sativa constituent, as an antipsychotic drug Brazilian Journal of Medical and Biological Research April 1, 2006
- The Impact of Cannabis Use on Cognitive Functioning in Patients With Schizophrenia: A Meta-analysis of Existing Findings and New Data in a First-Episode Sample Schizophrenia Bulletin July 25, 2010
- Cannabis Use Disorders in Schizophrenia: Effects on Cognition and Symptoms Schizophrenia Research May 18, 2010
- Neurocognitive performance during acute THC intoxication in heavy and occasional cannabis users. Journal of Psychopharmacology May 2009
- The temporal dynamics of relationships between cannabis, psychosis and depression among young adults with psychotic disorders: findings from a 10-month prospective study. Psychological Medicine July 1, 2007
and 3 more in the library