Ibotenic acid in Amanita muscaria spores and caps
F. C. Størmer, K. Janák, G. Koller
Mycologist August 1, 2004 DOI: 10.1017/s0269915x04003039 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Peer reviewed |
|---|---|
| Key points | Ibotenic acid was found in Amanita muscaria spores and caps, with the enol tautomer predominating (96:4 ratio). Muscimol was absent. Neither ibotenic acid, muscimol, nor extracts inhibited Bacillus subtilis growth at 50 nanomol. |
Abstract
Summary Ibotenic acid (α-amino-3-hydroxy-5-isoxazole acetic acid) was separated from spores and caps from Amanita muscaria by reversed phase high performance liquid chromatography and identified by flow injection analysis with mass spectrometric detection. The keto and enol tautomers of ibotenic acid were separated and their ratio of 96:4 in favour of the enol form was determined. On average the ibotenic acid content was 0.0054 ± 0.0010% of the spores and 0.017 ± 0.010% in fresh caps. Muscimol, the decarboxylated product from ibotenic acid, was neither detected in spores nor in caps. 50 nanomol of ibotenic acid, muscimol or extracts from spores or caps did not inhibit the growth of Bacillus subtilis.
Citations in the library
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- Toxicological Profiles of Poisonous, Edible, and Medicinal Mushrooms Mycobiology September 1, 2014
- Fungal Hallucinogens Psilocin, Ibotenic Acid, and Muscimol Therapeutic Drug Monitoring July 12, 2013
- Amanita muscaria: Ecology, Chemistry, Myths Encyclopedia September 2, 2021
- Classics in Chemical Neuroscience: Muscimol. ACS Chemical Neuroscience September 18, 2024
- Quantitative LC-QToF-MS Analysis of Mycochemicals in Amanita muscaria, Psilocybe spp. (Agaricomycetes), and Consumer Products. International journal of medicinal mushrooms 2025
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