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Opinion Mining of Erowid's Experience Reports on LSD and Psilocybin-Containing Mushrooms.

Ahmed Al-Imam, Riccardo Lora, Marek A Motyka, Erica Marletta, Michele Vezzaro, Jerzy Moczko, Manal Younus, Michal Michalak

Drug safety May 1, 2025 DOI: 10.1007/s40264-025-01530-z (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational study using natural language processing Peer reviewed
Sample size 2,188
Population Users of the Erowid forum who reported experiences with psilocybin-containing mushrooms or LSD
Topics LSD Psilocybin
Keywords Consciousness research Altered states Psychedelics Drug effects
Citations 1
Key findings Psilocybin mushroom reports emphasize introspection and time dilation, while LSD reports highlight cognitive disturbances and memory issues, with sentiment analysis showing model-dependent polarity differences.

Abstract

Psychedelics are gaining attention for their therapeutic potential in modern and personalized medicine. Online forums such as Erowid provide valuable user insights, but analyses of these experiences using natural language processing (NLP) remain scarce. This study aims to utilize NLP, including sentiment and lexicon analysis, to examine user-generated experience reports on psilocybin-containing mushrooms and LSD from the Erowid forum. Data from 2188 Erowid users (1161 psilocybin mushrooms and 1027 LSD) was collected via automated web scraping with XPath, CSS selectors, and Selenium WebDriver. The dataset included report titles, substances, and demographics. Sentiment analysis utilized BERT, RoBERTa, and VADER models. Preprocessing involved tokenization, lemmatization, part-of-speech tagging, and stop-word filtering. Lexicon analysis identified themes through recurring n-grams, visualized using Python. User demographics revealed comparable ages for psilocybin mushrooms (23.8 ± 0.9 years) and LSD users (20.0 ± 0.6 years), with a predominance of male users. The BERT model predominantly labeled experiences as negative (unfavorable), particularly for mushroom users (p = 0.001). VADER indicated more positive experiences for mushroom users (p < 0.001), while RoBERTa mainly classified experiences as negative or neutral. Significant gender differences were found only with VADER, where more male users expressed positive opinions about psilocybin mushrooms (74.09% versus 65.52%, p < 0.021). The VADER model yielded more polarized results, whereas RoBERTa's cautious classifications indicate its suitability for analyzing lengthy and complex psychedelic reports. Further, RoBERTa outperformed other transformer-based models, achieving the highest accuracy. Lexicon analysis revealed emotional, sensory, and temporal themes, with psilocybin reports emphasizing introspection and time dilation phenomenon, while LSD reports highlighted memory issues and cognitive disorientation. Sentiment analysis showed that VADER produced more polarized results, while RoBERTa offered cautious classifications with the highest accuracy. Lexicon analysis revealed shared themes, with mushroom reports focusing on introspection and time dilation perception, while those of LSD emphasized cognitive disturbances. This study highlights the value of these analyses in understanding psychedelic experiences, informing harm reduction, and guiding policy-making.

Comparable studies

Other observational and cohort studies on LSD, most cited first.

Study Year Design Participants
Increased Global Functional Connectivity Correlates with LSD-Induced Ego Dissolution. Human participants 2016 Observational cohort
Increased spontaneous MEG signal diversity for psychoactive doses of ketamine, LSD and psilocybin Humans 2017 Observational study
Classic psychedelic use is associated with reduced psychological distress and suicidality in the United States adult population. USA adult respondents from the National Survey on Drug Use and Health (2008-2012) 2015 Observational cohort n = 190,000
Psychedelics not linked to mental health problems or suicidal behavior: A population study Randomly selected United States adults 2015 Observational cohort n = 135,095
Whole-Brain Multimodal Neuroimaging Model Using Serotonin Receptor Maps Explains Non-linear Functional Effects of LSD. Healthy human participants 2018 Observational study with computational modeling

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