Synthesis of 131I derivatives of indolealkylamines for brain mapping
Jose A. Sintas, Arturo Alberto Vitale
Journal of Labelled Compounds and Radiopharmaceuticals August 1, 1997 DOI: 10.1002/(sici)1099-1344(199708)39:8<677::aid-jlcr9>3.0.co;2-g (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Peer reviewed |
|---|---|
| Citations | 12 |
| Key points | Reports the synthesis of six iodine-131-labeled indolealkylamines via a novel high-yield method, with full spectral characterization. The authors state these compounds are biologically important and can be used for brain mapping with SPECT technology. |
Abstract
The synthesis and spectral properties of new radioiodinated indolealkylamines like 2-[131I]-iodo-N,N-dimethyltryptamine, 2-[131I]-iodo-N-methyltryptamine, 2-[131I]-iodo-5-methoxy-N,N-dimethyltryptamine, 2-[131I]-iodio-5-hydroxy-N,N-dimethyltryptamine (2-[131I]-iodo-bufotenine), and 2-[131I]-iodo-tryptamine and the known 2-[131I]-iodo-N-acetly-5-methoxy-tryptamine (2-[131I]-iodo-melatonine) are described herein. There were synthesized by a high-yield novel method, and their spectral properties are fully described. These compounds are of biological importance and can be used for brain mapping with SPECT technology. © John Wiley & Sons, Ltd.
Citations in the library
Cited by 3
- Investigations into the polymorphic properties of N,N-dimethyltryptamine by X-ray diffraction and differential scanning calorimetry Microchemical Journal March 20, 2013
- Synthesis of a deuterium‐labelled standard of bufotenine (5‐HO‐DMT) Journal of Labelled Compounds and Radiopharmaceuticals October 1, 2007
- In vivo long-term kinetics of radiolabeled n,n-dimethyltryptamine and tryptamine. Journal of Nuclear Medicine June 2011
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