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Are ecstasy users biased toward endorsing somatic mental health symptoms? Results from a general community sample.

Amanda M George, Tim D Windsor, Bryan Rodgers

Psychopharmacology April 2011 DOI: 10.1007/s00213-010-2100-8 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Observational study using multiple indicator, multiple cause models Peer reviewed
Sample size 316
Population Current ecstasy users aged 24-30 years identified from a population-based Australian study
Measures Goldberg anxiety/depression symptom scales
Topics MDMA
Key findings No bias toward endorsing somatic symptoms was found with higher ecstasy use, both with and without adjustment for gender, cannabis, and meth/amphetamine use. The authors suggest other studies using alternate mental health measures should adopt this approach to test for somatic symptom endorsement bias.

Abstract

Whether the reported poorer mental health of ecstasy users is due to a bias in endorsement of somatic symptoms has been postulated, but rarely examined. The purpose of this study is to investigate whether levels of ecstasy use were associated with differential probabilities of endorsing somatic mental health symptoms. Current ecstasy users aged 24-30 years (n = 316) were identified from a population-based Australian study. Measures included frequency of ecstasy, meth/amphetamine, and cannabis use and the Goldberg anxiety/depression symptom scales. Multiple indicator, multiple cause models demonstrated no bias towards endorsing somatic symptoms with higher ecstasy use, both with and without adjustment for gender, cannabis, and meth/amphetamine use. Other studies using alternate measures of mental health should adopt this approach to determine if there is a bias in the endorsement of somatic symptoms among ecstasy users.

Comparable studies

Other observational and cohort studies on MDMA, most cited first.

Study Year Design Participants
Subjective Reports of the Effects of MDMA in a Clinical Setting Individuals who took MDMA in a clinical setting 1986 Observational study
Memory impairment in abstinent MDMA ("Ecstasy") users Abstinent MDMA users 1998 Observational cohort
Impaired cognitive performance in drug free users of recreational ecstasy (MDMA) Otherwise healthy young people 2000 Observational
The Psychological and Physiological Effects of MDMA on Normal Volunteers Older, more educated, drug-experienced individuals 1986 Observational cohort
Cognitive performance in recreational users of MDMA or 'ecstasy': evidence for memory deficits Young people who were regular or novice MDMA users, or non-users 1998 Observational cohort n = 30

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