Acute psychosis following ingestion of 'Rapture'.
Helen Austin, Erik Monasterio
Australasian Psychiatry December 2004 DOI: 10.1080/j.1440-1665.2004.02137.x (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Case study Case report Peer reviewed |
|---|---|
| Sample size | 1 |
| Population | A 20-year-old man with no prior psychiatric history |
| Interventions | cannabis nitrous oxide benzodiazepines |
| Duration | 6-month follow-up |
| Key findings | The authors report that a 20-year-old man with no prior psychiatric history developed a brief psychotic episode with persecutory delusions and auditory and visual hallucinations 12 hours after ingesting the dietary supplement 'Rapture' along with small amounts of cannabis and nitrous oxide. The episode resolved with benzodiazepines and did not recur over six months. The authors suggest that piperazine-containing 'herbal high' supplements may precipitate psychosis in vulnerable individuals. |
Abstract
To describe a brief psychotic episode associated with ingestion of a dietary supplement containing piperazine. A case report was undertaken. A 20-year-old man developed a brief psychotic episode associated with persecutory delusional beliefs and auditory and visual hallucinations, leading him to commit the offence of arson. This episode occurred 12 h following the ingestion of 'Rapture' in addition to small quantities of cannabis and nitrous oxide, in a young man with no prior psychiatric history. This episode resolved with the use of benzodiazepines and 6 months later he has had no recurrence of psychiatric symptoms. Given the reported mechanism of action of the 'herbal high' dietary supplements, it would seem possible that they may be able to precipitate a psychotic episode in vulnerable individuals. With the increasing use of these substances, it is important for clinicians to be alert to this possibility.
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