Impact of Psilocybin on Peripheral Cytokine Production
Dana D. DiRenzo, Jamie Perin, Erika Darrah, Frederick S. Barrett, Lisa Christopher‐stine, Roland R. Griffiths
Psychedelic Medicine February 28, 2024 DOI: 10.1089/psymed.2023.0039 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Preliminary study Peer reviewed |
|---|---|
| Intervention | Psilocybin |
| Duration | ≤1-week post-psilocybin |
| Topics | Psilocybin |
| Keywords | Peripheral Production economics Cytokine |
| Citations | 4 |
| Registration | NCT01988311 |
| Key points | Psilocybin may transiently increase cytokine production within one week, though not consistently across patient populations. |
Abstract
This preliminary study suggests that a transient increase in cytokine production ≤1-week postpsilocybin may be found, although not consistently across patient populations. More broadly, peripheral cytokine production is possibly altered by psilocybin administration. ClinicalTrials.gov Identifier: NCT01988311.
Citations in the library
Cited by 4
- Are we hallucinating or can psychedelic drugs modulate the immune system to control inflammation? British Journal of Pharmacology July 28, 2025
- Narrating the psychoneuroimmunomodulatory properties of serotonin 5-HT2A receptor psychedelics from a transdiagnostic perspective. Acta Neuropsychiatrica July 25, 2025
- Advancing cancer neuroscience through stress modulation: Interdisciplinary potential of psilocybin and ketamine General Hospital Psychiatry February 25, 2026
- Are psychedelics anti-inflammatory? A systematic review and meta-analysis of studies examining the immunomodulatory effects of serotonergic psychedelics. Brain, Behavior, and Immunity September 28, 2026
Cites 16
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- Psilocybin can occasion mystical-type experiences having substantial and sustained personal meaning and spiritual significance Psychopharmacology July 7, 2006
- Effects of Psilocybin-Assisted Therapy on Major Depressive Disorder JAMA Psychiatry November 4, 2020
- Human hallucinogen research: guidelines for safety. Journal of Psychopharmacology July 1, 2008
- Mystical experiences occasioned by the hallucinogen psilocybin lead to increases in the personality domain of openness Journal of Psychopharmacology September 28, 2011
and 11 more in the library