Sleep quality and adolescent default mode network connectivity
Sarah M. Tashjian, Diane Goldenberg, M. Monti, A. Galván
Social Cognitive and Affective Neuroscience February 7, 2018 DOI: 10.1093/scan/nsy009 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational study Peer reviewed |
|---|---|
| Sample size | 45 |
| Population | Human adolescents ages 14-18 |
| Duration | 14 days of actigraphy |
| Measures | resting state functional connectivity, actigraphy |
| Topics | Default mode network |
| Key findings | Worse sleep quality, but not shorter sleep duration, was associated with weaker intrinsic connectivity within the default mode network at rest in adolescents. The authors suggest sleep quality is a relatively unexplored index related to adolescent brain function in a network that contributes to behavioral maturation. |
Abstract
Abstract Sleep suffers during adolescence and is related to academic, emotional and social behaviors. How this normative change relates to ongoing brain development remains unresolved. The default mode network (DMN), a large-scale brain network important for complex cognition and socioemotional processing, undergoes intra-network integration and inter-network segregation during adolescence. Using resting state functional connectivity and actigraphy over 14 days, we examined correlates of naturalistic individual differences in sleep duration and quality in the DMN at rest in 45 human adolescents (ages 14–18). Variation in sleep quality, but not duration, was related to weaker intrinsic DMN connectivity, such that those with worse quality sleep evinced weaker intra-network connectivity at rest. These novel findings suggest sleep quality, a relatively unexplored sleep index, is related to adolescent brain function in a network that contributes to behavioral maturation and undergoes development during adolescence.
Comparable studies
Other observational and cohort studies on default mode network, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| A default mode of brain function Normal adult human brain | 2001 | Observational study | |
| Resting-State Functional Connectivity Reflects Structural Connectivity in the Default Mode Network Healthy subjects | 2008 | Observational cohort | |
| Meditation experience is associated with increased cortical thickness Participants with extensive Insight meditation experience and matched controls | 2005 | Observational cohort | n = 20 |
| Meditation experience is associated with differences in default mode network activity and connectivity Experienced meditators and matched meditation-naive controls | 2011 | Observational cohort | |
| The precuneus/posterior cingulate cortex plays a pivotal role in the default mode network: Evidence from a partial correlation network analysis Healthy subjects | 2008 | Observational study |
Citations in the library
Cited by 5
- Neurobehavioral pathways linking socioeconomic status hardship to suicide risk versus resilience in young adolescents: the roles of sleep health and default mode network connectivity. Translational Psychiatry November 24, 2025
- Latent Default Mode Network Connectivity Patterns: Associations With Sleep Health and Adolescent Psychopathology Brain and Behavior May 1, 2025
- Getting a Good Night's Sleep: Associations Between Sleep Duration and Parent-Reported Sleep Quality on Default Mode Network Connectivity in Youth. Journal of Adolescent Health June 2023
- Altered Coactive Micropattern Connectivity in the Default-Mode Network during the Sleep-Wake Cycle Neural Plasticity November 23, 2020
- Default mode network anatomy and function is linked to pediatric concussion recovery
Cites 8
- A default mode of brain function Proceedings of the National Academy of Sciences January 16, 2001
- The precuneus/posterior cingulate cortex plays a pivotal role in the default mode network: Evidence from a partial correlation network analysis Neuroimage June 13, 2008
- Patterns of Brain Activity Supporting Autobiographical Memory, Prospection, and Theory of Mind, and Their Relationship to the Default Mode Network Journal of Cognitive Neuroscience July 6, 2009
- Decoupling of the brain's default mode network during deep sleep Proceedings of the National Academy of Sciences June 19, 2009
- Age-related alterations in default mode network: Impact on working memory performance Neurobiology of Aging August 1, 2008
and 3 more in the library