Default Mode Network Maturation and Environmental Adversities During Childhood.
Keila Rebello, Luciana M Moura, Walter H L Pinaya, Luis A Rohde, João R. Sato
Chronic Stress 2018 DOI: 10.1177/2470547018808295 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Review Peer reviewed |
|---|---|
| Topics | Default mode network |
| Keywords | Connectivity Environmental exposure Typical brain development |
| Key findings | The authors propose that changes in default mode network development may represent a potential allostatic neural feature reflecting the embodiment of environmental circumstances, particularly chronic childhood adversity. They also highlight the challenge of disentangling neurodevelopmental connectivity changes from those related to environmental conditions in early life. |
Abstract
Default mode network (DMN) plays a central role in cognition and brain disorders. It has been shown that adverse environmental conditions impact neurodevelopment, but how these conditions impact in DMN maturation is still poorly understood. This article reviews representative neuroimaging functional studies addressing the interactions between DMN development and environmental factors, focusing on early life adversities, a critical period for brain changes. Studies focused on this period of life offer a special challenge: to disentangle the neurodevelopmental connectivity changes from those related to environmental conditions. We first summarized the literature on DMN maturation, providing an overview of both typical and atypical development patterns in childhood and early adolescence. Afterward, we focused on DMN changes associated with chronic exposure to environmental adversities during childhood. This summary suggests that changes in DMN development could be a potential allostatic neural feature associated with an embodiment of environmental circumstances. Finally, we discuss about some key methodological issues that should be considered in paradigms addressing environmental adversities and open questions for future investigations.
Comparable studies
Other narrative reviews on default mode network, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| The Brain's Default Mode Network | 2015 | Review | |
| Default Mode Network Activity and Connectivity in Psychopathology | 2012 | Review | |
| 20 years of the default mode network: A review and synthesis | 2023 | Review | |
| On the relationship between the “default mode network” and the “social brain” | 2012 | Review | |
| The default mode network and social understanding of others: what do brain connectivity studies tell us Healthy subjects, with some studies on patients with autism and psychopathy | 2014 | Review |
Citations in the library
Cited by 2
Cites 12
- Default Mode Network Activity and Connectivity in Psychopathology Annual Review of Clinical Psychology March 29, 2012
- Functional connectivity of default mode network components: Correlation, anticorrelation, and causality Human Brain Mapping January 24, 2008
- On the relationship between the “default mode network” and the “social brain” Frontiers in Human Neuroscience 2012
- Fractionating the Default Mode Network: Distinct Contributions of the Ventral and Dorsal Posterior Cingulate Cortex to Cognitive Control Journal of Neuroscience March 2, 2011
- Decoupling of the brain's default mode network during deep sleep Proceedings of the National Academy of Sciences June 19, 2009
and 7 more in the library