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Mindfulness-Based Cognitive Therapy for Patients With Depression Decreases the Need for Outpatient Visits.

Robert G. Bota, Jessica Hazen, Ryan Tieu, Andrei Novac

The Primary Care Companion For CNS Disorders August 25, 2016 DOI: 10.4088/pcc.16m01985 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Retrospective study Peer reviewed
Sample size 142
Population Patients with a history of 2 or more episodes of major depressive disorder (recurrent MDD) or other mood disorders who completed MBCT group sessions between January 1, 2010, and December 31, 2013
Intervention Mindfulness-based cognitive therapy (MBCT)
Duration MBCT group sessions over 3 years (2010-2013); outcomes compared in the year after MBCT versus before
Topics Depression Meditation
Key points MBCT did not significantly change medication use in either recurrent MDD or nonrecurrent MDD patients. Recurrent MDD patients who participated in MBCT had significant reductions in all calls and visits (P = .0068) and psychiatric visits (P = .0026) in the year after MBCT compared with before, suggesting MBCT may decrease the need for care regardless of medication changes.

Abstract

To determine if the use of mindfulness-based cognitive therapy (MBCT) in patients with a history of 2 or more episodes of major depressive disorder and other mood disorders will decrease the need for medication management and other interventions and will also decrease the need for outpatient services and the overall cost of treatment. The study patients completed MBCT group sessions between January 1, 2010, and December 31, 2013. Patients who had 2 or more episodes of major depressive disorder (recurrent MDD) were categorized into a group. The remaining patients with other mood disorders were placed in a comparison group. The mean differences in drug treatments and hospital utilizations between the recurrent MDD and nonrecurrent MDD group were compared. Wald P values and 95% CIs were obtained for both adjusted and unadjusted estimated mean differences. Covariates were adjusted for age at start of MBCT, gender, and race/ethnicity. The final sample consisted of 142 patients (93 recurrent MDD and 49 others). There was no significant difference in the effect of MBCT on medication changes between recurrent MDD patients and nonrecurrent MDD patients. Recurrent MDD patients who participated in MBCT experienced reduction in all calls and visits (P = .0068) and less psychiatric visits (P = .0026) in the year after MBCT when compared with the visits before the intervention. This study evaluated the effectiveness of MBCT in reducing the need for additional psychiatric services. The study evaluated patients who received MBCT over 3 years and demonstrated that MBCT decreased the need for care regardless of medication changes. The results raise the question of whether MBCT allows patients to respond to situations more skillfully or if MBCT itself decreases depressive symptoms. The limitations of this study include a small sample size, patient selection, and its design as a retrospective study. However, this study may have implications as a treatment strategy that may be generalizable to other clinics and patient populations.

Comparable studies

Other observational and cohort studies on depression, most cited first.

Study Year Design Participants
Metacognitive awareness and prevention of relapse in depression: Empirical evidence. Residually depressed patients and nondepressed controls; recovered depressed patients 2002 Observational cohort with intervention components
Psilocybin for treatment-resistant depression: fMRI-measured brain mechanisms. Patients with treatment-resistant depression 2017 Observational cohort n = 19
Antidepressant effects of a single dose of ayahuasca in patients with recurrent depression: a preliminary report Patients with a depressive disorder 2015 Observational study
Concomitant BDNF and sleep slow wave changes indicate ketamine-induced plasticity in major depressive disorder Patients with treatment-resistant major depressive disorder 2012 Observational cohort n = 30
Altered peripheral immune profiles in treatment-resistant depression: response to ketamine and prediction of treatment outcome Healthy controls and actively depressed patients with treatment-resistant depression... 2017 Observational cohort n = 59

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