Impact of Mindfulness Based Stress Reduction Therapy on Myocardial Function and Endothelial Dysfunction in Female Patients with Microvascular Angina
Bong‐Joon Kim, In Suk Cho, Kyoung-Im Cho
Journal of Cardiovascular Ultrasound 2017 DOI: 10.4250/jcu.2017.25.4.118 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Pre-post intervention study Longitudinal Peer reviewed |
|---|---|
| Sample size | 34 |
| Population | Female patients with microvascular angina (mean age 52.2 ± 13.8 years) |
| Interventions | Mindfulness-based stress reduction (MBSR) anti-anginal medication |
| Duration | 8 weeks |
| Measures | Global longitudinal strain (GLS), flow-mediated dilatation (FMD), Symptom Checklist 90 Revised |
| Topics | Meditation |
| Citations | 17 |
| Key points | The authors conclude that an 8-week MBSR program has beneficial impacts on myocardial and endothelial function in women with microvascular angina. Changes in GLS and FMD correlated with changes in most stress parameters, though the abstract does not report the magnitude or direction of the GLS and FMD changes. |
Abstract
Background: Mindfulness-based stress reduction (MBSR) is a structured group program that employs mindfulness meditation to alleviate suffering associated with physical, psychosomatic, and psychiatric disorders. In this study, we investigate the impact of MBSR on left ventricular (LV) and endothelial function in female patients with microvascular angina.
Methods: A total of 34 female patients (mean age 52.2 ± 13.8 years) diagnosed with microvascular angina underwent a MBSR program with anti-anginal medication for 8 weeks. The global longitudinal strain (GLS) of the LV was used as a parameter to assess myocardial function and reactive brachial flow-mediated dilatation (FMD) was used to assess endothelial function. Symptoms were analyzed by the Symptom Checklist 90 Revised to determine emotional stress. Changes in GLS and FMD between baseline and post-MBSR were analyzed.
Results: = 0.340) and with the changes in most stress parameters.
Conclusion: MBSR has beneficial impacts on myocardial and endothelial function in female patients with microvascular angina.
Comparable studies
Other non-randomized and open-label trials on meditation, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Mindfulness-Based Stress Reduction in Relation to Quality of Life, Mood, Symptoms of Stress, and Immune Parameters in Breast and Prostate Cancer Outpatients Early-stage breast and prostate cancer patients | 2003 | Pre-post intervention study | n = 59 |
| Exploring self‐compassion and empathy in the context of mindfulness‐based stress reduction (MBSR) Community sample | 2010 | Pre-post intervention study | |
| Mindfulness-Based Stress Reduction Lowers Psychological Distress In Medical Students Second-year medical students | 2003 | Prospective nonrandomized cohort-controlled study | n = 302 |
| Intensive meditation training, immune cell telomerase activity, and psychological mediators. Retreat participants and matched controls | 2011 | Controlled trial with wait-list control group | n = 60 |
| The Effectiveness of Mindfulness Training for Children with ADHD and Mindful Parenting for their Parents Children aged 8-12 with ADHD and their parents | 2011 | Within-group waitlist controlled trial | n = 22 |
Citations in the library
Cited by 4
- Mindfulness-based stress reduction combined with early cardiac rehabilitation improves negative mood states and cardiac function in patients with acute myocardial infarction assisted with an intra-aortic balloon pump: a randomized controlled trial Frontiers in Cardiovascular Medicine May 31, 2023
- Three potential neurovascular pathways driving the benefits of mindfulness meditation for older adults. Frontiers in Aging Neuroscience 2023
- Mindfulness-based intervention in patients with persistent pain in chest (MIPIC) of non-cardiac cause: a feasibility randomised control study. Open heart May 2022
- The protective effect of mindfulness and compassion meditation practices on ageing: Hypotheses, models and experimental implementation. Ageing Research Reviews October 1, 2021
Cites 9
- Effectiveness of a meditation-based stress reduction program in the treatment of anxiety disorders American Journal of Psychiatry July 1, 1992
- Short-term autonomic and cardiovascular effects of mindfulness body scan meditation Annals of Behavioral Medicine November 15, 2006
- Mindfulness Meditation, Anxiety Reduction, and Heart Disease Family & Community Health 2003
- Mindfulness-based stress reduction program in coronary heart disease: A randomized control trial International Journal of Yoga August 26, 2015
- One year pre-post intervention follow-up of psychological, immune, endocrine and blood pressure outcomes of mindfulness-based stress reduction (MBSR) in breast and prostate cancer outpatients. Brain, Behavior, and Immunity November 2007
and 4 more in the library