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Intracerebral Hemorrhage with Multiple Intracranial Arterial Stenoses in a Synthetic Cannabinoid "Spice" User.

Seckin Aydin, Odhan Yuksel, Aysegul Esen Aydin, Osman Kizilkilic, Suat Erol Celik

Asian journal of neurosurgery 2018 DOI: 10.4103/ajns.ajns_48_16 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Case study Case report Peer reviewed
Sample size 1
Population A 23-year-old man admitted with altered consciousness after synthetic cannabinoid use
Keywords Intracerebral hemorrhage Side effect Synthetic cannabinoid
Key findings The authors report a large frontal intracerebral hematoma extending into the ventricular system in a 23-year-old man after synthetic cannabinoid use, with cerebral angiography showing multiple intracranial arterial stenoses (MIAS). They propose an association between synthetic cannabinoid use and both the hemorrhage and MIAS, noting the patient recovered well with treatment and remained stable at follow-up.

Abstract

Synthetic cannabinoids (spice), which are used frequently worldwide, are more potent than herbal compounds and also have more side effects in comparison. A 23-year-old male was admitted to the emergency unit with altered consciousness. There was no sign of trauma, and his medical history did not reveal any chronic illness. Computed tomography revealed a large frontal hematoma extending to the ventricular system. The outcomes of cerebral angiography were consistent with multiple intracranial arterial stenoses (MIAS) which can also be seen after cannabis usage. The patient made a good recovery with treatment, and during the follow-up, his medical condition was stable. In addition to the psychological symptoms, encephalopathy, ischemia, and seizures have also been described as side effects of synthetic cannabinoids. This paper reports an intracerebral hematoma due to synthetic cannabinoids and its association with MIAS.

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