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How to make psychedelic-assisted therapy safer

Daniel Villiger

Cambridge Quarterly of Healthcare Ethics September 27, 2024 DOI: 10.1017/s0963180124000604 (opens in new tab)

Study at a glance

AI-extracted from the abstract
Characteristics Theoretical or philosophical paper Peer reviewed
Topics Psychedelic-assisted therapy
Keywords Psychedelics Entheogenic therapy Psychedelic medicine Patient safety Patient protection Therapeutic safety Risk mitigation Harm reduction Safeguards Well-being Therapeutic support Patient support Clinical support Session support Companion support Caregiving Patient autonomy Ethical considerations Patient rights Self-determination
Citations 10
Key points Argues that bringing a close person to the psychedelic session is a highly effective and feasible safety measure overlooked in the literature.

Abstract

Classic serotonergic psychedelics are experiencing a clinical revival, which has also revived ethical debates about psychedelic-assisted therapy. A particular issue here is how to prepare and protect patients from the vulnerability that the psychedelic state creates. This paper first examines how this vulnerability manifests itself, revealing that it results from an impairment of autonomy: psychedelics diminish decision-making capacity, reduce controllability, and limit resistance to external influences. It then analyzes the strengths and weaknesses of five safety measures proposed in the literature, what aspect of the patient’s vulnerability they seek to reduce, and how they can be optimized. The analysis shows that while preparatory sessions, advance directives, and specific training and oversight are useful, starting with a lower dosage and no therapy is less so. Finally, the paper presents a safety measure that has been overlooked in the literature but could be highly effective and feasible: bringing a close person to the psychedelic session

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