Impact of yoga based lifestyle intervention on psychological stress and quality of life in the parents of children with retinoblastoma.
Shilpa Bisht, Bhavna V. Chawla, Madhuri R Tolahunase, Richa Mishra, Rima Dada
Annals of Neurosciences April 2019 DOI: 10.5214/ans.0972.7531.260206 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Single-arm prospective clinical trial Peer reviewed |
|---|---|
| Population | Parents of children affected with retinoblastoma |
| Interventions | pranayama dhyana relaxation techniques lectures and films on yoga interactive sessions and individualized advice |
| Duration | 12 weeks |
| Measures | WHOQOL-BREF |
| Topics | Depression |
| Keywords | Childhood cancer Quality of life Retinoblastoma |
| Key findings | The authors report that a 12-week yoga-based lifestyle intervention significantly improved psychological stress and all WHOQOL-BREF quality-of-life domains in parents of children with retinoblastoma, and increased BDNF, DHEA-sulfate, and sirtuin 1 while decreasing cortisol and IL-6. They propose the intervention may serve as a beneficial therapy for stress management and coping in this population. |
Abstract
Childhood cancers are associated with a psychological burden to the parents and hence, decline their mental and physical health and overall quality of life. The purpose of the present study is to investigate the impact of 12-weeks yoga based lifestyle intervention on psychological stress and quality of life in the parents of children affected with retinoblastoma. Single arm prospective clinical trial conducted from October 2015 to October 2017 at the Laboratory for Molecular Reproduction and Genetics, Department of Anatomy, All India Institute of Medical Sciences, New Delhi, India. A pre-tested 12-weeks yoga based lifestyle intervention included asanas (physical postures), pranayama (breathing exercises), dhyana (meditation), relaxation techniques, lectures and films on yoga, interactive sessions and individualized advice was administered to the participants. 12-weeks of yoga based lifestyle intervention programme leads to a significant improvement in psychological stress and overall quality of life in the parents of retinoblastoma patients. There was a significant improvement in all the domains (physical health, psychological health, social relationships, and environment) of WHOQOL-BREF from baseline (day 0) to 12-weeks of yoga based lifestyle intervention. Yoga based lifestyle intervention also led to a significant increase in the levels of brain derived neurotrophic factor, dehydroepiandrosterone sulphate, sirtuin 1 and decreased the cortisol and IL-6 levels. Yoga based lifestyle intervention reduced the severity of psychological stress and resulted in improvement in overall quality of life and upregulation in levels of systemic biomarkers of neuroplasticity. YBLI may serve as a beneficial therapy and may also act as an effective medium for better stress management to develop better coping strategies in the parents of retinoblastoma patients.
Comparable studies
Other non-randomized and open-label trials on depression, most cited first.
Citations in the library
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