Neural correlates of a mindfulness-based intervention in anorexia nervosa.
Tomomi Noda, Masanori Isobe, Ryo Mishima, Keima Tose, Michiko Kawabata, Toshihiko Aso, Shisei Tei, Shun'ichi Noma, Toshiya Murai
BJPsych Open February 2, 2023 DOI: 10.1192/bjo.2022.637 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Preprint Peer reviewed |
|---|---|
| Sample size | 21 |
| Population | Patients with anorexia nervosa |
| Interventions | Mindfulness-based intervention Acceptance strategy |
| Topics | Anxiety Meditation |
| Keywords | Anorexia nervosa Acceptance Emotion regulation |
| Key points | The authors report that a mindfulness-based intervention was associated with reduced activity in the amygdala, anterior cingulate cortex, putamen, caudate, orbital gyrus, middle frontal gyrus, posterior cingulate cortex, and precuneus during a weight-related anxiety regulation task in 21 anorexia patients. They propose these findings offer insight into the neural mechanisms by which mindfulness-based intervention may ameliorate anorexia nervosa. |
Abstract
We examined the neural underpinnings of the effects of mindfulness on anxiety in anorexia nervosa using functional magnetic resonance imaging in 21 anorexia patients. We used a functional magnetic resonance imaging task designed to induce weight-related anxiety and asked participants to regulate their anxiety either using or not using an acceptance strategy. Our results showed reduced activity in the amygdala, anterior cingulate cortex, putamen, caudate, orbital gyrus, middle frontal gyrus, posterior cingulate cortex and precuneus following a mindfulness-based intervention. The present study provides new insight regarding the neural mechanisms underlying the effect of mindfulness-based intervention in ameliorating anorexia nervosa.
Citations in the library
Cites 2
- The precuneus/posterior cingulate cortex plays a pivotal role in the default mode network: Evidence from a partial correlation network analysis Neuroimage June 13, 2008
- Resting-state fMRI functional connectivity and mindfulness in clinical and non-clinical contexts: A review and synthesis. Neuroscience & Biobehavioral Reviews February 22, 2022