Coffee consumption decreases the connectivity of the posterior Default Mode Network (DMN) at rest.
Maria Picó Pérez, Ricardo Magalhães, Madalena Esteves, Rita Vieira, Teresa C Castanho, Liliana Amorim, Mafalda Sousa, Ana Coelho, Pedro S Moreira, Rodrigo A Cunha, Nuno Sousa
Frontiers in Behavioral Neuroscience 2023 DOI: 10.3389/fnbeh.2023.1176382 (opens in new tab)
Study at a glance
AI-extracted from the abstract| Characteristics | Observational neuroimaging study (resting-state fMRI functional connectivity) Peer reviewed |
|---|---|
| Population | A group of habitual coffee drinkers |
| Interventions | Coffee Caffeine |
| Topics | Default mode network |
| Keywords | Coffee Connectomics Executive control network Resting-state |
| Key findings | Coffee consumption decreased connectivity of the posterior default mode network and between somatosensory/motor networks and the prefrontal cortex, while connectivity increased in higher visual network nodes and the right executive control network. Caffeine intake alone replicated only the posterior DMN effect, which the authors argue disentangles caffeine's neurochemical effects from the experience of drinking coffee. |
Abstract
Habitual coffee consumers justify their life choices by arguing that they become more alert and increase motor and cognitive performance and efficiency; however, these subjective impressions still do not have a neurobiological correlation. Using functional connectivity approaches to study resting-state fMRI data in a group of habitual coffee drinkers, we herein show that coffee consumption decreased connectivity of the posterior default mode network (DMN) and between the somatosensory/motor networks and the prefrontal cortex, while the connectivity in nodes of the higher visual and the right executive control network (RECN) is increased after drinking coffee; data also show that caffeine intake only replicated the impact of coffee on the posterior DMN, thus disentangling the neurochemical effects of caffeine from the experience of having a coffee.
Comparable studies
Other experimental studies on default mode network, most cited first.
| Study | Year | Design | Participants |
|---|---|---|---|
| Functional connectivity of default mode network components: Correlation, anticorrelation, and causality Healthy subjects | 2008 | Observational study using resting-state fMRI and seed correlation analysis | |
| Patterns of Brain Activity Supporting Autobiographical Memory, Prospection, and Theory of Mind, and Their Relationship to the Default Mode Network Healthy subjects | 2009 | Experimental study using fMRI | |
| Dynamic reconfiguration of the default mode network during narrative comprehension Human subjects | 2016 | Experimental study | |
| Broadband Cortical Desynchronization Underlies the Human Psychedelic State Healthy human participants | 2013 | Experimental study | |
| The brain on art: intense aesthetic experience activates the default mode network Human observers | 2012 | Observational study with fMRI and behavioral analysis |
Citations in the library
Cited by 3
- The Psychedelic Renaissance: A Catholic Perspective. Linacre Q September 15, 2024
- Ketamine-induced analgesia and dissociation show distinct behavioral and neural correlates Neuropsychopharmacology July 20, 2026
- Using caffeine as a chemical means to induce flow states. Neuroscience & Biobehavioral Reviews April 1, 2024